Blaustein M P
Science. 1971 Apr 23;172(3981):391-3. doi: 10.1126/science.172.3981.391.
Isolated superior cervical ganglia of rats accumulate more calcium during preganglionic stimulation than do unstimulated controls; uptake of calcium-45 is approximately doubled by stimulation of 12 impulses per second. The extra uptake is markedly reduced by a high concentration of magnesium, but not by mecamylamine hydrochloride or tetraethylammonium chloride, although all three agents eliminate the postsynaptic action potential. Uptake of calcium-45 is also greatly increased by a high external concentration of potassium.
与未受刺激的对照组相比,大鼠分离出的颈上神经节在节前刺激期间积累更多的钙;每秒12次冲动的刺激使钙-45的摄取量增加约一倍。高浓度的镁可显著降低额外的摄取量,但盐酸美加明或氯化四乙铵则不能,尽管这三种药物都能消除突触后动作电位。细胞外高浓度的钾也会使钙-45的摄取量大幅增加。