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1
Chlorpromazine: concentrations in plasma, excretion in urine and duration of effect.氯丙嗪：血浆浓度、尿排泄及作用持续时间。
Proc R Soc Med. 1971 Mar;64(3):285-9. doi: 10.1177/003591577106400323.
2
Urinary excretion of chlorpromazine metabolites following single doses and in steady-state conditions.单次给药及稳态条件下氯丙嗪代谢物的尿排泄情况。
Res Commun Chem Pathol Pharmacol. 1971 May;2(3):330-8.
3
The assay of chlorpromazine and metabolites in blood, urine, and other tissues.血液、尿液及其他组织中氯丙嗪及其代谢物的测定。
CRC Crit Rev Clin Lab Sci. 1971 Sep;2(3):347-91. doi: 10.3109/10408367109151312.
4
Factors affecting chlorpromazine plasma levels in psychiatric patients.影响精神病患者氯丙嗪血药浓度的因素。
Arch Gen Psychiatry. 1970 Mar;22(3):209-15. doi: 10.1001/archpsyc.1970.01740270017002.
5
Comparison of injectable haloperidol and chlorpromazine.注射用氟哌啶醇与氯丙嗪的比较。
Am J Psychiatry. 1972 Jul;129(1):78-81. doi: 10.1176/ajp.129.1.78.
6
[Analysis of the consistency of the Forrest test with the dosage of chlorpromazine administered and the amount of the drug excreted daily in the urine (total fraction)].
Psychiatr Pol. 1970 Jul-Aug;4(4):429-34.
7
Studies of delayed-action medication. V. Plasma levels and urinary excretion of four different dosage forms of chlorpromazine.长效药物研究。五、四种不同剂型氯丙嗪的血浆浓度及尿排泄情况
Clin Pharmacol Ther. 1970 Jan-Feb;11(1):49-59. doi: 10.1002/cpt197011149.
8
Total excretion of 3H-chlorpromazine and 3H-prochlorperazine in chronically dosed animals: balance sheet.长期给药动物中3H-氯丙嗪和3H-奋乃静的总排泄量：收支平衡表。
Adv Biochem Psychopharmacol. 1974;9(0):347-56.
9
Pharmacokinetics of chlorpromazine after single and chronic dosage.单次及长期给药后氯丙嗪的药代动力学
Clin Pharmacol Ther. 1977 Apr;21(4):437-48. doi: 10.1002/cpt1977214437.
10
[Level of free and bound chlorpromazine fractions in the blood and urine during chlorpromazine treatment].[氯丙嗪治疗期间血液及尿液中游离和结合氯丙嗪组分的水平]
Psychiatr Pol. 1970 Jul-Aug;4(4):435-42.

引用本文的文献

1
Repurposing host-based therapeutics to control coronavirus and influenza virus.基于宿主的治疗药物的再利用以控制冠状病毒和流感病毒。
Drug Discov Today. 2019 Mar;24(3):726-736. doi: 10.1016/j.drudis.2019.01.018. Epub 2019 Jan 31.
2
The relationship of plasma chlorpromazine to its 7-hydroxy and sulphoxide metabolites in a large population of chronic schizophrenics.大样本慢性精神分裂症患者的血浆氯丙嗪与其 7-羟基代谢物和亚砜代谢物的关系。
Br J Clin Pharmacol. 1974 Oct;1(5):425-30. doi: 10.1111/j.1365-2125.1974.tb00281.x.
3
Antipsychotic pharmacotherapy and orthostatic hypotension: identification and management.抗精神病药物治疗与直立性低血压：识别与管理。
CNS Drugs. 2011 Aug;25(8):659-71. doi: 10.2165/11591710-000000000-00000.
4
Tardive dyskinesia and pimozide.迟发性运动障碍与匹莫齐特
Proc R Soc Med. 1977;70(Suppl 10):34-8. doi: 10.1177/0035915777070S1007.
5
Emergency treatment of psychotic symptoms. Pharmacokinetic considerations for antipsychotic drugs.精神病症状的紧急治疗。抗精神病药物的药代动力学考量。
Clin Pharmacokinet. 1995 Jun;28(6):494-504. doi: 10.2165/00003088-199528060-00007.
6
Effects of chlorpromazine and promazine on the visual aftereffects of tilt and movement.氯丙嗪和异丙嗪对倾斜及运动视觉后效的影响。
Psychopharmacology (Berl). 1983;79(1):49-57. doi: 10.1007/BF00433016.
7
Effect of chlorpromazine and some of its metabolites on synthesis and turnover of catecholamines formed from 14 C-tyrosine in mouse brain.氯丙嗪及其某些代谢产物对小鼠脑内由¹⁴C-酪氨酸形成的儿茶酚胺合成及更新的影响。
Psychopharmacologia. 1972;26(2):155-60. doi: 10.1007/BF00422102.
8
Serum levels of thioridazine in psychiatric patients and healthy volunteers.精神病患者和健康志愿者的硫利达嗪血清水平。
Eur J Clin Pharmacol. 1973 Oct;6(3):181-6. doi: 10.1007/BF00558283.
9
Mute of malady.疾病的沉默
Br Med J. 1973 Mar 31;1(5856):755-6.
10
Clinical use of psychotherapeutic drugs. I. Antipsychotic and antimanic drugs.精神治疗药物的临床应用。I. 抗精神病药和抗躁狂药。
Drugs. 1972;4(5):321-60. doi: 10.2165/00003495-197204050-00001.

本文引用的文献

1
FURTHER STUDIES OF CHLORPROMAZINE METABOLISM AND RELAPSE RATE.
J Psychiatr Res. 1965 May;3:27-35. doi: 10.1016/0022-3956(65)90012-9.
2
NON-POLAR URINARY METABOLITES OF CHLORPROMAZINE IN MALE SCHIZOPHRENICS.男性精神分裂症患者中氯丙嗪的非极性尿液代谢物
J Psychiatr Res. 1964 Dec;2:299-305. doi: 10.1016/0022-3956(64)90015-9.
3
Inter-patient variation in chlorpromazine metabolism.氯丙嗪代谢的患者间差异。
Exp Med Surg. 1965;23(2):278-87.
4
Plasma levels of chlorpromazine and some of its relatively non-polar metabolites in psychiatric patients.精神病患者血浆中氯丙嗪及其一些相对非极性代谢物的水平。
Life Sci. 1968 Jan 1;7(1):9-17. doi: 10.1016/0024-3205(68)90356-1.
5
The physiological disposition of chlorpromazine in the rat and dog.氯丙嗪在大鼠和狗体内的生理处置
Proc Soc Exp Biol Med. 1970 May;134(1):314-8. doi: 10.3181/00379727-134-34784.
6
Factors affecting chlorpromazine plasma levels in psychiatric patients.影响精神病患者氯丙嗪血药浓度的因素。
Arch Gen Psychiatry. 1970 Mar;22(3):209-15. doi: 10.1001/archpsyc.1970.01740270017002.
7
Studies of delayed-action medication. V. Plasma levels and urinary excretion of four different dosage forms of chlorpromazine.长效药物研究。五、四种不同剂型氯丙嗪的血浆浓度及尿排泄情况
Clin Pharmacol Ther. 1970 Jan-Feb;11(1):49-59. doi: 10.1002/cpt197011149.
8
Dose effects of chlorpromazine on human sleep.
Psychopharmacologia. 1969;14(4):342-8. doi: 10.1007/BF02190118.

Chlorpromazine: concentrations in plasma, excretion in urine and duration of effect.

作者信息

Curry S H

出版信息

Proc R Soc Med. 1971 Mar;64(3):285-9. doi: 10.1177/003591577106400323.

DOI:10.1177/003591577106400323
PMID:5551485
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1811516/
Abstract
摘要