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镁缺乏时大鼠胃内的细胞群体动力学及生化变化

Cell population kinetics and biochemical changes in the rat stomach during magnesium deficiency.

作者信息

Artizzu M

出版信息

Biochem Exp Biol. 1979;15(3):217-22.

PMID:555674
Abstract

Cell populations of rat stomach have been counted following varying (4-60 days) periods of magnesium-deficient diet and compared to a control group. The activity of beta-glucuronidase and the serotonin concentration were assayed in magnesium-deficient and control rats within four weeks. In the rat stomach the magnesium deficiency produces a numerical decrease in mucous cells, especially marked after 3 and 4 weeks. At this time, the activity of beta-glucuronidase decreases significantly. The concentration of serotonin increases at an earlier time and this increase coincides with the onset of the typical erythema occurring in magnesium-deficient rats.

摘要

在给予大鼠不同时长(4 - 60天)的缺镁饮食后,对其胃内细胞群进行了计数,并与对照组进行比较。在四周内对缺镁大鼠和对照大鼠的β-葡萄糖醛酸酶活性和血清素浓度进行了测定。在大鼠胃中,缺镁会导致黏液细胞数量减少,在3周和4周后尤为明显。此时,β-葡萄糖醛酸酶的活性显著降低。血清素浓度在更早的时候就会升高,这种升高与缺镁大鼠出现的典型红斑的发作时间一致。

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