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年轻自发性高血压大鼠血清中的游离脂肪酸模式

The free fatty acid pattern in blood serum in young spontaneously hypertensive rats.

作者信息

Michailov M L

出版信息

Biochem Exp Biol. 1979;15(3):286-9.

PMID:555680
Abstract

An investigation on the free fatty acid (FFA) profile in blood serum, using liquid gas chromatography, has been carried out on young (8-9 week-old) spontaneously hypertensive rats (SHR). A significative increase in the level of unsaturated FFA was found in SHR in comparison to their controls. The deviations in the composition of the FFA spectrum found were elevation of the polyunsaturated fatty acids: hexadecanoic acid (C16:2), linoleic acid (C18:2), linolenic acid (C18:3), eicosadienoic acid (C20:2), eicosatrienoic acid (C20:3), eicosapentaenoic acid (C20:5). The differences between FFA profile in SHR and control group can reflect genetically controlled variables.

摘要

利用液相气相色谱法对年轻（8 - 9周龄）自发性高血压大鼠（SHR）血清中的游离脂肪酸（FFA）谱进行了研究。与对照组相比，发现SHR中不饱和脂肪酸水平显著升高。所发现的FFA谱组成偏差为多不饱和脂肪酸升高：十六碳二烯酸（C16:2）、亚油酸（C18:2）、亚麻酸（C18:3）、二十碳二烯酸（C20:2）、二十碳三烯酸（C20:3）、二十碳五烯酸（C20:5）。SHR与对照组FFA谱之间的差异可反映基因控制的变量。

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