Singer P, Voigt S, Gödicke W, Pfeiffer D, Baumann R
Cor Vasa. 1980;22(5):327-34.
The fatty acid pattern of serum triglycerides and FFA in normal untrained subjects, normotensive athletes, patients with labile and stable essential hypertension as well as in hypertensives with overweight and mild hypertriglyceridemia has been evaluated by gas liquid chromatography. The most striking differences revealed the linoleic acid in triglycerides being increased in athletes and in patients with labile hypertension in comparison with normotensive untrained controls and patients with stable hypertension. On the basis of these data an enhanced need of polyunsaturated fatty acids corresponding to probands with high physical activity has been assumed in patients with an early stage of essential hypertension. The differences of arachidonic acid were not so distinct. The results can be relevant with regard to the pathogenetic role of prostaglandin precursors in the development and course of essential hypertension and atherosclerosis.
通过气液色谱法评估了正常未经训练的受试者、血压正常的运动员、不稳定型和稳定型原发性高血压患者以及超重和轻度高甘油三酯血症高血压患者血清甘油三酯和游离脂肪酸的脂肪酸模式。最显著的差异表明，与血压正常的未经训练的对照组和稳定型高血压患者相比，运动员和不稳定型高血压患者甘油三酯中的亚油酸增加。基于这些数据，假设原发性高血压早期患者对多不饱和脂肪酸的需求增加，这与具有高体力活动的先证者相对应。花生四烯酸的差异没有那么明显。这些结果可能与前列腺素前体在原发性高血压和动脉粥样硬化的发生和发展过程中的致病作用有关。
