Jablonski M, Tomlinson E
Ophthalmology. 1979 Dec;86(12):2112-4. doi: 10.1016/s0161-6420(79)35302-7.
Sixty-four patients who did not respond adequately to passive conventional occlusion were treated with active pleoptic therapy, and followed with orthoptic therapy when fusion potential was demonstrated. Patients ranged in age from 4 to 17 years, and ranged in visual acuity from 20/30 to 20/100. Seventeen patients had some fusion prior to starting pleoptics. All 64 patients achieved an immediate post-therapy acuity of 20/30 or better; 25 were fusing and demonstrated some stereopsis. Twenty-seven patients were followed for a period of one to ten years, including the 25 patients who were fusing at completion of therapy. Twenty-four (88%) maintained visual acuity of 20/30 or better. All fused either normally or with ARC. Three patients, whose visual acuity dropped to 20/50, had no fusion. Only one patient who had fusion at the completion of therapy was unable to maintain it. We conclude, therefore, that pleoptics retains values in the treatment of amblyopic patients with steady and unsteady central fixation, in those situations where conventional occlusion in unsuccessful.
64例对被动传统遮盖治疗反应不佳的患者接受了主动视刺激疗法治疗，当显示有融合潜力时采用斜视矫正疗法进行后续治疗。患者年龄在4至17岁之间，视力范围为20/30至20/100。17例患者在开始视刺激疗法之前有一定程度的融合。所有64例患者治疗后即时视力均达到20/30或更好；25例实现融合并显示出一定的立体视。27例患者随访1至10年，包括治疗结束时实现融合的25例患者。24例（88%）维持视力在20/30或更好。所有患者要么正常融合，要么呈异常视网膜对应融合。3例视力降至20/50的患者没有融合。仅1例在治疗结束时实现融合的患者未能维持融合状态。因此，我们得出结论，在传统遮盖治疗失败的情况下，视刺激疗法在治疗中央注视稳定和不稳定的弱视患者中仍具有价值。
