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丙胺卡因对乌头碱诱发心律失常的影响。

Prilocaine effect on aconitine-induced arrhythmias.

作者信息

Quevedo M, Pérez-Olea J, Pino C

出版信息

Acta Physiol Lat Am. 1978;28(4-5):201-7.

PMID:555837
Abstract

Prilocaine, a synthetic tertiary amine with local anesthetic properties, suppressed aconitine-induced atrial and ventricular arrhythmias in the cat. In normal animals, prilocaine decreased the heart rate. In the group of successfully treated arrhythmic cats as well as in normal animals, the drug increased the blood pressure, while the equally effective antiarrhythmic drug, lidocaine, did decrease blood pressure.

摘要

丙胺卡因是一种具有局部麻醉特性的合成叔胺,它可抑制乌头碱诱发的猫心房和心室心律失常。在正常动物中,丙胺卡因会降低心率。在成功治疗心律失常的猫组以及正常动物中,该药物会升高血压,而同样有效的抗心律失常药物利多卡因则会降低血压。

相似文献

1
Prilocaine effect on aconitine-induced arrhythmias.丙胺卡因对乌头碱诱发心律失常的影响。
Acta Physiol Lat Am. 1978;28(4-5):201-7.
2
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