[The toxicity of aconitine and its analogs and their effects on cardiac contractile function].
作者信息
Zhou Y P, Liu W H, Zeng G Y, Chen D H, Li H Y, Song W L
出版信息
Yao Xue Xue Bao. 1984 Sep;19(9):641-6.
PMID:6536174
Abstract
摘要
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[The toxicity of aconitine and its analogs and their effects on cardiac contractile function].[乌头碱及其类似物的毒性及其对心脏收缩功能的影响]
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Disruption of the intracellular Ca2+ homeostasis in the cardiac excitation-contraction coupling is a crucial mechanism of arrhythmic toxicity in aconitine-induced cardiomyocytes.乌头碱诱导的心肌细胞中，细胞内钙离子稳态在心脏兴奋-收缩偶联过程中的破坏是心律失常毒性的关键机制。
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