Costantin L L
J Gen Physiol. 1971 Aug;58(2):117-30. doi: 10.1085/jgp.58.2.117.
Potassium-induced contractures were studied in single fibers from the semitendinosus muscle of Rana pipiens. Contractures elicited by solutions containing 60-117 mM potassium and 120 mM chloride were biphasic, consisting of a rapid initial contraction with a duration at 23 degrees C of less than 1 sec followed by a slow response with a duration of many seconds. At 13 degrees C, the initial response was greatly prolonged so that the two responses virtually fused into a single smooth contracture. Membrane potential in high potassium, high chloride solutions underwent a transient peak depolarization, probably as a result of time-dependent changes in membrane conductance during depolarization. It is proposed that this complex time course of depolarization gives rise to the biphasic contracture response.
对豹蛙半腱肌单纤维中的钾诱导挛缩进行了研究。由含60 - 117 mM钾和120 mM氯的溶液引发的挛缩是双相的，包括在23℃下持续时间小于1秒的快速初始收缩，随后是持续数秒的缓慢反应。在13℃时，初始反应大大延长，以至于这两个反应几乎融合成一个单一的平滑挛缩。在高钾、高氯溶液中，膜电位经历了一个短暂的峰值去极化，这可能是去极化过程中膜电导随时间变化的结果。有人提出，这种复杂的去极化时间过程导致了双相挛缩反应。
