Jones J R, de Hempel P A, Kemmann E, Tenner M S
Obstet Gynecol. 1977 Jan;49(1 suppl):9-11.
A report of a patient with amenorrhea and galactorrhea who was shown, by tomopneumoencephalogram, to have an empty sella is presented. Endocrinologic testing revealed only a blunted human growth hormone response to insulin-induced hypoglycemia and acyclicity of plasma gonadotropins. Thyroid testing, ACTH, and metopirone responses were normal. In addition, plasma prolactin levels were found to be within the normal range. Most significantly, after the pneumoencephalogram the patient's menses returned and have continued at regular monthly intervals for 6 months. During this time there has been a significant decrease in the galactorrhea. This is the first patient described with an empty sella and galactorrhea. The clinical and endocribologic aspects of the empty sella are discussed.
本文报告了一名闭经和溢乳患者，经气脑造影显示为空蝶鞍。内分泌检查仅发现对胰岛素诱导的低血糖的人生长激素反应迟钝以及血浆促性腺激素无周期性变化。甲状腺检查、促肾上腺皮质激素（ACTH）和甲吡酮反应均正常。此外，发现血浆催乳素水平在正常范围内。最显著的是，气脑造影后患者月经恢复，并连续6个月每月规律来潮。在此期间，溢乳明显减少。这是首例报道的空蝶鞍合并溢乳患者。本文还讨论了空蝶鞍的临床和内分泌方面。
