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Interaction of palladium (II) with DNA.

作者信息

Pillai C K, Nandi U S

出版信息

Biochim Biophys Acta. 1977 Jan 3;474(1):11-6. doi: 10.1016/0005-2787(77)90209-x.

Abstract

The nature of interaction of palladium (II) with calf thymus DNA was studied using viscometry, ultraviolet, visible and infrared spectrophotometry and optical rotatory disperison and circular dichroism measurements. The results indicate that Pd(II) interacts with both the phosphate and bases of DNA. The ORD/CD data indicate that the binding of Pd(II) to DNA brings about considerable conformational changes in DNA.

摘要

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