Raskin N H, Prusiner S
Neurology. 1977 Jan;27(1):43-6. doi: 10.1212/wnl.27.1.43.
Nosologic uncertainty about carotidynia has arisen, in part, because the syndrome was initially classified as an atypical facial neuralgia. More recently, carotidynia has been characterized as a recurring vascular neck pain, often accompanied by carotid tenderness and soft tissue swelling and sometimes by vascular headaches. We now report that drugs useful in the prophylaxis of migraine appear to be effective in carotidynia. Eight women (ages 39 to 77) with unilateral, episodic neck pain of 1 to 19 years' duration have been observed for periods ranging from 7 months to 6 years. All experienced marked relief in the intensity and frequency of their pain syndromes after the administration of methysergide, ergonovine maleate, propranolol, or nortriptyline. No patient had evidence of arteritis. The responsiveness of both migraine headaches and carotidynia to similar drugs suggests a common pathophysiologic mechanism.
关于颈动脉痛的疾病分类存在不确定性，部分原因是该综合征最初被归类为非典型面部神经痛。最近，颈动脉痛被描述为一种反复发作的颈部血管性疼痛，常伴有颈动脉压痛和软组织肿胀，有时还伴有血管性头痛。我们现在报告，用于预防偏头痛的药物似乎对颈动脉痛有效。我们观察了8名女性（年龄39至77岁），她们患有单侧发作性颈部疼痛，病程为1至19年，观察期从7个月到6年不等。所有患者在服用麦角新碱、马来酸麦角新碱、普萘洛尔或去甲替林后，疼痛综合征的强度和频率都有明显缓解。没有患者有动脉炎的证据。偏头痛和颈动脉痛对类似药物的反应性表明存在共同的病理生理机制。
