Schrijen F, Gille J P
Pflugers Arch. 1977 Jan 17;367(3):229-33. doi: 10.1007/BF00581359.
Circulatory changes were studied in 9 mongrel dogs during partial extracorporeal circulation from the right atrium to the carotid and/or femoral artery. The bypass circuit consisted of a membrane oxygenator and a roller pump. Cardiac output and arterial pressure decreased during bypass, but changed little when extracorporeal flow (EF) was increased from 1/10 to 3/4 of control cardiac output. Right atrial and pulmonary wedge pressures were lower than control. Total blood flow was equal to control when EF was 1/2 of the control cardiac output, and exceeded control flow at 3/4. Such enhanced venous return presumably resulted from sympathetic stimulation via atrial mechanoreceptors.
在9只杂种狗进行从右心房到颈动脉和/或股动脉的部分体外循环期间，对循环变化进行了研究。旁路循环由一个膜式氧合器和一个滚压泵组成。在旁路期间心输出量和动脉压下降，但当体外循环血流量（EF）从对照心输出量的1/10增加到3/4时，变化很小。右心房压和肺楔压低于对照。当EF为对照心输出量的1/2时，总血流量等于对照，在3/4时超过对照流量。这种增强的静脉回流可能是通过心房机械感受器的交感神经刺激所致。
