Cohen H B, Gambill A F, Eggers G W
Anesth Analg. 1977 Jan-Feb;56(1):136-9. doi: 10.1213/00000539-197701000-00034.
An acute episode of pulmonary edema may occur in association with head injury. This is due to the elevation of systemic blood pressure, to maintain cerebral circulation in the presence of increasing intracranial pressure (ICP). In these instances, the pulmonary edema arises as a pathophysiologic, neurohemodynamic response to the intracranial disease. This response has been produced experimentally, and 2 case reports described this problem clinically. If such patients with increased ICP could be treated immediately with antihypertensive drugs, pulmonary edema might be prevented and the high mortality rate decreased.
肺水肿的急性发作可能与头部损伤有关。这是由于在颅内压(ICP)升高的情况下,为维持脑循环而导致全身血压升高。在这些情况下,肺水肿是作为对颅内疾病的一种病理生理、神经血液动力学反应而出现的。这种反应已通过实验产生,并且有2例病例报告从临床角度描述了这个问题。如果能立即用降压药治疗这些颅内压升高的患者,或许可以预防肺水肿并降低高死亡率。