Wong M L, Kaplan S, Dunkle L M, Stechenberg B W, Feigin R D
J Pediatr. 1977 Apr;90(4):532-7. doi: 10.1016/s0022-3476(77)80361-2.
A diagnosis of leptospirosis was confirmed in nine children who were admitted to St. Louis Children's Hospital during the past 54 months. Epidemiologic, clinical, cultural, and serologic data which were obtained emphasize (1) the high incidence of urban cases; (2) contact with dogs as the most likely source of infection; and (3) that serotypes other than Leptospira icterohaemorrhagiae may produce severe clinical disease. Unusual or previously unreported manifestations of leptospirosis including acalculous cholecystitis, pancreatitis, abdominal causalgia, desquamating skin rashes, and infarction of the extremities which were noted in these children are discussed.
在过去54个月里,圣路易斯儿童医院收治的9名儿童被确诊为钩端螺旋体病。所获取的流行病学、临床、培养和血清学数据强调了:(1)城市病例的高发病率;(2)与狗接触是最可能的感染源;(3)出血性黄疸型钩端螺旋体以外的血清型可能会引发严重的临床疾病。本文还讨论了这些儿童中出现的钩端螺旋体病的异常或先前未报告的表现,包括无结石性胆囊炎、胰腺炎、腹部灼痛、脱屑性皮疹和肢体梗死。