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跨膜稳态筛分

Steady-state sieving across membranes.

作者信息

Bresler E H, Wendt R P, Mason E A

出版信息

Science. 1971 May 21;172(3985):858-9. doi: 10.1126/science.172.3985.858.

DOI:10.1126/science.172.3985.858
PMID:5572909
Abstract

The constraint of steady-state operation for sieving or ultrafiltration across membranes greatly restricts possible theoretical mechanisms. Effective sieving in the steady state requires the coexistence of a removal mechanism with the rejection mechanism. These points are illustrated without elaborate mathematics by a model of membranes in a series array with intervening compartments. This model also shows that in certain regimes the structure of the first membrane alone determines the overall sieving characteristics of the array.

摘要

跨膜筛分或超滤的稳态操作限制极大地制约了可能的理论机制。稳态下的有效筛分要求去除机制与截留机制同时存在。通过带有中间隔室的串联膜阵列模型,无需复杂数学推导即可说明这些要点。该模型还表明,在某些情况下,仅第一个膜的结构就决定了整个阵列的筛分特性。

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J Cell Biol. 1972 Jun;53(3):777-87. doi: 10.1083/jcb.53.3.777.
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Equations for membrane transport. Experimental and theoretical tests of the frictional model.膜运输方程。摩擦模型的实验与理论测试。
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