Richey E J, Brock W E, Kliewer I O, Jones E W
Am J Vet Res. 1977 Feb;38(2):169-70.
Ten 30-month-old cattle (group 2) were inoculated with Anaplasma marginale 6 months after the latent A marginale infection was eliminated by oral chlortetracycline therapy. In addition, 4 cattle (group 1) with no record of infection and 4 cattle (group 3) of equivalent age previously vaccinated with a killed antigen were similarly inoculated. Moderate to severe clinical signs of acute anaplasmosis occurred in the group 1 (previously uninfected) cattle, whereas only 1 of the chlortetracycline-treated cattle (group 2) and none of the vaccinated cattle (group 3) had clinical evidence of disease.
10头30月龄的牛(第2组)在通过口服金霉素疗法消除了边缘无形体潜伏感染6个月后,接种了边缘无形体。此外,对4头无感染记录的牛(第1组)和4头先前接种过灭活抗原的同龄牛(第3组)进行了类似接种。第1组(先前未感染)的牛出现了中度至重度急性无形体病的临床症状,而金霉素治疗的牛(第2组)中只有1头发病,接种疫苗的牛(第3组)则无发病迹象。