醋酸甲羟孕酮在人体中对催乳素的释放作用。
The release of prolactin by medroxy-progesterone acetate in human subjects.
作者信息
Chaudhury R R, Chompootaweep S, Dusitsin N, Friesen H, Tankeyoon M
出版信息
Br J Pharmacol. 1977 Mar;59(3):433-4. doi: 10.1111/j.1476-5381.1977.tb08397.x.
Medroxyprogesterone acetate an injectable contraceptive when administered to four lactating women at a dose of 150 mg every three months significantly raised prolactin levels over those observed in four control women. Prolactin levels were higher at all times during 4-17 weeks in the drug-treated women, irrespective of whether the samples were collected before or after suckling. It was also observed that while suckling clearly released prolactin in both groups the difference was greater in the women receiving the injection, indicating that the drug enhanced the release of prolactin in response to the suckling stimulus.
醋酸甲羟孕酮是一种注射用避孕药，给四名哺乳期妇女每三个月注射150毫克后，其催乳素水平比四名对照妇女显著升高。在药物治疗组妇女中，4至17周期间的催乳素水平在各个时间点均较高，无论样本是在哺乳前还是哺乳后采集。还观察到，虽然两组中哺乳均能明显释放催乳素，但接受注射的妇女中差异更大，这表明该药物增强了催乳素对哺乳刺激的释放反应。
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