Lutz R A, Märki H H, Weder H G
J Clin Chem Clin Biochem. 1977 Feb;15(2):57-67.
The literature on the determination and the meaning of androgen binding to plasma proteins is reviewed. Because of the high affinity for the active androgens the sex hormone binding globulin (SHBG) is of considerable importance. The blood level of this globulin varies according to sex, age, medicamentation and pathological conditions. The influence of protein binding on the metabolism and mechanism of action of androgens is discussed and the hypotheses of several authors are compared.
本文综述了雄激素与血浆蛋白结合的测定及其意义的相关文献。由于对活性雄激素具有高亲和力，性激素结合球蛋白（SHBG）具有相当重要的意义。这种球蛋白的血药浓度因性别、年龄、药物治疗和病理状况而异。本文讨论了蛋白结合对雄激素代谢和作用机制的影响，并比较了几位作者的假说。
