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雌激素作为癌症患者的网状内皮系统刺激剂。

Oestrogen as a reticuloendothelial stimulant in patients with cancer.

作者信息

Magarey C J, Baum M

出版信息

Br Med J. 1971 May 15;2(5758):367-70. doi: 10.1136/bmj.2.5758.367.

DOI:10.1136/bmj.2.5758.367
PMID:5575972
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1795795/
Abstract

Stimulation of reticuloendothelial activity may benefit patients with cancer. Oestrogenic compounds are known to stimulate reticuloendothelial phagocytic activity in animals and a similar effect is demonstrated in patients.The depression of reticuloendothelial phagocytic activity which follows radiotheraphy in the treatment of cancer can be prevented by the simultaneous administration of stilboestrol. Possibly this could be associated with a more favourable response to therapy, and a controlled trial is needed to establish this.

摘要

刺激网状内皮系统活性可能对癌症患者有益。已知雌激素化合物可刺激动物的网状内皮系统吞噬活性，且在患者中也证实了类似效果。在癌症治疗中，放疗后出现的网状内皮系统吞噬活性降低可通过同时给予己烯雌酚来预防。这可能与对治疗的更有利反应相关，需要进行对照试验来证实这一点。

相似文献

1
Oestrogen as a reticuloendothelial stimulant in patients with cancer.雌激素作为癌症患者的网状内皮系统刺激剂。
Br Med J. 1971 May 15;2(5758):367-70. doi: 10.1136/bmj.2.5758.367.
2
The effects of oestrogen: androgen interaction on the reticulo-endothelial system and reproductive tract.雌激素与雄激素相互作用对网状内皮系统及生殖道的影响。
J Endocrinol. 1966 Feb;34(2):163-78. doi: 10.1677/joe.0.0340163.
3
The effect of operative treatment, chemotherapy, and oestrogens on the phagocytic activity of the reticuloendothelial system.手术治疗、化疗和雌激素对网状内皮系统吞噬活性的影响。
Acta Chir Scand. 1972;138(6):557-61.
4
Dose-related reticuloendothelial system stimulation by diethylstilbestrol.己烯雌酚与剂量相关的网状内皮系统刺激作用。
J Reticuloendothel Soc. 1976 Dec;20(6):457-60.
5
Reversal by diethyl-stilboestrol of the depressant effect of cortisone on the phagocytic activity of the reticulo-endothelial system.己烯雌酚对可的松抑制网状内皮系统吞噬活性作用的逆转
Nature. 1957 Jun 1;179(4570):1137-8. doi: 10.1038/1791137a0.
6
[Hormone therapy in carcinoma of the prostate].[前列腺癌的激素治疗]
Wien Klin Wochenschr. 1966 Jul 22;78(29):512-4 passim.
7
The mechanism of oestrogen stimulation of reticuloendothelial activity.雌激素刺激网状内皮系统活性的机制。
J Anat. 1969 Jan;104(Pt 1):190.
8
Observations on the activity of the reticuloendothelial system in estradiol- and diethylstilbestrol-treated rats.对用雌二醇和己烯雌酚处理的大鼠网状内皮系统活性的观察
Endokrinologie. 1973 Jan;61(1):152-5.
9
Plasma testosterone: an accurate monitor of hormone treatment in prostatic cancer.血浆睾酮：前列腺癌激素治疗的精确监测指标。
Br J Urol. 1973 Dec;45(6):668-77. doi: 10.1111/j.1464-410x.1973.tb12238.x.
10
[Estrogens and phagocytic function of the reticuloendothelial system].[雌激素与网状内皮系统的吞噬功能]
C R Seances Soc Biol Fil. 1957;151(7):1326-31.

引用本文的文献

1
Oestrogens and host resistance.雌激素与宿主抵抗力。
J R Soc Med. 1980 Mar;73(3):161-4. doi: 10.1177/014107688007300302.
2
Reticuloendothelial activity and cancer.网状内皮系统活性与癌症
Br Med J. 1971 Jun 5;2(5761):588-9. doi: 10.1136/bmj.2.5761.588-d.
3
Morphological responses of prostatic carcinoma to testosterone in organ culture.前列腺癌在器官培养中对睾酮的形态学反应。
Br J Cancer. 1972 Oct;26(5):388-94. doi: 10.1038/bjc.1972.51.
4
The control of cancer spread by the reticuloendothelial system.网状内皮系统对癌症扩散的控制。
Ann R Coll Surg Engl. 1972 Apr;50(4):238-55.
5
Immunosuppressive effect of estrogen on thymic dependent lymphocytic blastogenesis.雌激素对胸腺依赖性淋巴细胞增殖的免疫抑制作用。
Urol Res. 1974;2(2):69-71. doi: 10.1007/BF00554589.
6
Effect of stimulation of the host defense system by coenzyme Q 10 on dibenzpyrene-induced tumors and infection with Friend leukemia virus in mice.辅酶Q10对宿主防御系统的刺激对二苯并芘诱导的小鼠肿瘤及Friend白血病病毒感染的影响。
Proc Natl Acad Sci U S A. 1973 Feb;70(2):390-4. doi: 10.1073/pnas.70.2.390.
7
[Effect of various oral contraceptives on the phagocytic activity of the reticulo-endothelial system (author's transl)].各种口服避孕药对网状内皮系统吞噬活性的影响（作者译）
Arch Gynakol. 1974 May 14;216(3):257-71. doi: 10.1007/BF00668622.
8
Hypothesis: breast cancer regression under oestrogen therapy.假设：雌激素治疗下的乳腺癌消退。
Br Med J. 1973 Aug 25;3(5877):446-50. doi: 10.1136/bmj.3.5877.446.
9
Letter: Variations in leucocyte count during menstrual cycle.信件：月经周期中白细胞计数的变化
Br Med J. 1975 Jul 12;3(5975):102. doi: 10.1136/bmj.3.5975.102.
10
Effects of oestrogens and pregnancy on the distribution of sheep erythrocytes and the antibody response in mice.雌激素和妊娠对绵羊红细胞分布及小鼠抗体反应的影响。
Clin Exp Immunol. 1975 Apr;20(1):179-86.

本文引用的文献

1
The role of the reticuloendothelial system in the host reaction to neoplasia.网状内皮系统在宿主对肿瘤形成的反应中的作用。
Cancer Res. 1961 Oct;21:1281-300.
2
Cancer treatment: immunologic and chemotherapeutic interrelationships.癌症治疗：免疫与化疗的相互关系。
JAMA. 1961 Nov 18;178:723-6. doi: 10.1001/jama.1961.73040460001007.
3
Production of metastases by treatment with carcinostatic agents. I. Effects of carcinostatic agents on the host.用抗癌剂治疗产生转移。I. 抗癌剂对宿主的影响。
Cancer Res. 1961 Nov;21:1396-9.
4
OESTROGEN: THE NATURAL STIMULANT OF BODY DEFENCE.雌激素：身体防御的天然刺激物。
J Endocrinol. 1964 Oct;30:277-91. doi: 10.1677/joe.0.0300277.
5
COMBINATION THERAPY WITH CYCLOPHOSPHAMIDE AND ZYMOSAN ON A SPONTANEOUS MAMMARY CANCER IN MICE.环磷酰胺与酵母聚糖联合治疗小鼠自发性乳腺癌
Cancer Res. 1964 May;24:652-4.
6
IMMUNOLOGY OF EXPERIMENTAL TUMORS.实验性肿瘤的免疫学
Annu Rev Med. 1964;15:167-86. doi: 10.1146/annurev.me.15.020164.001123.
7
Experimental studies on Mitomycin C. 4. Zymosan and the R. E. S.丝裂霉素C的实验研究。4. 酵母聚糖与网状内皮系统
Growth. 1961 Sep;25:249-63.
8
Protective activity of fractions of tubercle bacilli against isologous tumours in mice.结核杆菌各组分对小鼠同源肿瘤的保护作用。
Nature. 1961 Jun 3;190:889-91. doi: 10.1038/190889a0.
9
[Influence of sex hormones on the stimulation of the phagocytic function of the reticuloendothelial system induced by inoculation of the Calmette-Guerin bacillus (BCG) in the mouse].[性激素对卡介苗接种诱导小鼠网状内皮系统吞噬功能刺激的影响]
C R Seances Soc Biol Fil. 1960;154:1994-2001.
10
Stimulation of host defense against experimental cancer. II. Temporal and reversal studies of the zymosan effect.宿主对实验性癌症防御的刺激。II. 酵母聚糖效应的时间及逆转研究。
Cancer Res. 1959 Jul;19(6, Part 1):673-8.