雌激素作为癌症患者的网状内皮系统刺激剂。
Oestrogen as a reticuloendothelial stimulant in patients with cancer.
作者信息
Magarey C J, Baum M
出版信息
Br Med J. 1971 May 15;2(5758):367-70. doi: 10.1136/bmj.2.5758.367.
Abstract
Stimulation of reticuloendothelial activity may benefit patients with cancer. Oestrogenic compounds are known to stimulate reticuloendothelial phagocytic activity in animals and a similar effect is demonstrated in patients.The depression of reticuloendothelial phagocytic activity which follows radiotheraphy in the treatment of cancer can be prevented by the simultaneous administration of stilboestrol. Possibly this could be associated with a more favourable response to therapy, and a controlled trial is needed to establish this.
摘要
刺激网状内皮系统活性可能对癌症患者有益。已知雌激素化合物可刺激动物的网状内皮系统吞噬活性，且在患者中也证实了类似效果。在癌症治疗中，放疗后出现的网状内皮系统吞噬活性降低可通过同时给予己烯雌酚来预防。这可能与对治疗的更有利反应相关，需要进行对照试验来证实这一点。
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