Panagopoulos P G, Tatooles C J, Aberdeen E, Waterston D J, Carter R E
Thorax. 1971 Mar;26(2):137-44. doi: 10.1136/thx.26.2.137.
Nine hundred and thirty-six consecutive cases of closure of a patent ductus arteriosus in infants and children are reported. Among 789 without any other cardiac anomalies there were 11 deaths, seven of these with severe congenital anomalies other than cardiovascular. There was one incomplete closure. The deaths in this series were mostly associated with additional congenital cardiac anomalies. Forty-eight of the 59 who died had additional cardiac anomalies. Forty-seven of the deaths were in infants. For 691 patients over the age of 1 year the hospital mortality rate was less than 0·5%. Ligation of the ductus using two ligatures of thick plaited silk (1·2 mm diameter) was the technique used in 99% of these cases. There were four cases of recanalization or inadequate ligation but all four survived. This technique seems an acceptable one for the closure of a patent ductus arteriosus.
报告了936例婴幼儿和儿童动脉导管未闭闭合的连续病例。在789例无其他心脏异常的病例中，有11例死亡，其中7例除心血管异常外还患有严重先天性异常。有1例闭合不完全。该系列中的死亡大多与其他先天性心脏异常有关。59例死亡病例中有48例伴有其他心脏异常。47例死亡发生在婴儿期。对于691例1岁以上的患者，医院死亡率低于0.5%。在99%的病例中，采用两根粗编织丝线（直径1.2毫米）结扎动脉导管的技术。有4例再通或结扎不充分，但所有4例均存活。这种技术似乎是一种可接受的动脉导管未闭闭合方法。
