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异种主动脉瓣的保存与功能:一项实验研究

Preservation and function of heterologous aortic valves. An experimental study.

作者信息

Gunning A J, Meade J B

出版信息

Thorax. 1971 Mar;26(2):179-83. doi: 10.1136/thx.26.2.179.

DOI:10.1136/thx.26.2.179
PMID:5576535
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1019124/
Abstract

Heterologous aortic valves are used in many clinics as replacements for diseased human aortic and mitral valves. These valves possess all the advantages of homologous aortic valves and are more easily available to the surgeon. The heterologous valve also provides a greater choice of valve size than does the homograft; this can be of importance when replacing the mitral valve. Heterograft valves, like homografts, are usually preserved for periods ranging from a few days to a few months before insertion into a patient. Four methods of preservation, described, are currently in use. This study compares the effects of these four methods of preservation when pig valves are transplanted into the dog's aorta.

摘要

异种主动脉瓣在许多临床中被用作病变的人体主动脉瓣和二尖瓣的替代品。这些瓣膜具有同种主动脉瓣的所有优点,并且外科医生更容易获得。与同种移植瓣膜相比,异种瓣膜在瓣膜尺寸上也提供了更多选择;在置换二尖瓣时这可能很重要。与同种移植瓣膜一样,异种移植瓣膜在植入患者体内之前通常要保存几天到几个月。目前正在使用所描述的四种保存方法。本研究比较了将猪瓣膜移植到狗的主动脉中时这四种保存方法的效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6b7/1019124/3010984d7d69/thorax00116-0046-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6b7/1019124/be005a98f968/thorax00116-0046-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6b7/1019124/951882490154/thorax00116-0046-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6b7/1019124/3010984d7d69/thorax00116-0046-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6b7/1019124/be005a98f968/thorax00116-0046-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6b7/1019124/951882490154/thorax00116-0046-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6b7/1019124/3010984d7d69/thorax00116-0046-c.jpg

相似文献

1
Preservation and function of heterologous aortic valves. An experimental study.异种主动脉瓣的保存与功能:一项实验研究
Thorax. 1971 Mar;26(2):179-83. doi: 10.1136/thx.26.2.179.
2
Mitral valve replacement with transplant valves.
J Thorac Cardiovasc Surg. 1970 Jul;60(1):13-25.
3
[Preparation of homologous and heterologous heart valve transplants using an improved freeze drying device].[使用改进的冷冻干燥装置制备同种和异种心脏瓣膜移植物]
Langenbecks Arch Chir. 1967;318(3):202-8. doi: 10.1007/BF01438872.
4
Implantation of homologous and heterologous aortic valves in prosthetic vascular tubes.同种和异种主动脉瓣在人工血管中的植入。
Thorax. 1969 Mar;24(2):142-7. doi: 10.1136/thx.24.2.142.
5
Assessment of incompetence in canine aortic and pulmonary valve grafts and comparison of some methods of valve preservation.犬主动脉瓣和肺动脉瓣移植物功能不全的评估及一些瓣膜保存方法的比较。
J Cardiovasc Surg (Torino). 1977 Sep-Oct;18(5):505-8.
6
Heterologous aortic valves for mitral replacement. Methods of preparation and preservation and operative technique.
J Thorac Cardiovasc Surg. 1970 Apr;59(4):489-95.
7
Porcine aortic valves for replacement of human heart valves.
J Cardiovasc Surg (Torino). 1973;Spec No:425-9.
8
Gamma-radiation of heart valves at 4 degrees C; a comparative study using techniques of histochemistry and electron and light microscopy.4℃下心脏瓣膜的γ射线辐射;一项使用组织化学、电子显微镜和光学显微镜技术的对比研究。
Thorax. 1973 Jan;28(1):95-101. doi: 10.1136/thx.28.1.95.
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[Comparative evaluation of different methods of sterilization of allo- and xenovalves under experimental conditions].[实验条件下同种和异种瓣膜不同灭菌方法的比较评估]
Eksp Khir Anesteziol. 1974 Mar-Apr(2):35-8.
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[Biochemical changes in heterologous aortic valve transplants following application of various sterilization methods].[应用各种灭菌方法后异种主动脉瓣移植的生化变化]
Langenbecks Arch Chir. 1969;325:1183-5. doi: 10.1007/BF01256095.

引用本文的文献

1
Pathology of the formalin-treated heterograft porcine aortic valve in the mitral position.二尖瓣位甲醛处理的异种移植猪主动脉瓣的病理学
Thorax. 1972 Jul;27(4):401-9. doi: 10.1136/thx.27.4.401.
2
Gamma-radiation of heart valves at 4 degrees C; a comparative study using techniques of histochemistry and electron and light microscopy.4℃下心脏瓣膜的γ射线辐射;一项使用组织化学、电子显微镜和光学显微镜技术的对比研究。
Thorax. 1973 Jan;28(1):95-101. doi: 10.1136/thx.28.1.95.

本文引用的文献

1
THE BEHAVIOUR OF HOMOTRANSPLANTED AORTIC VALVES IN THE DOG.
Br J Surg. 1965 Jul;52:549-52. doi: 10.1002/bjs.1800520716.
2
An evaluation of aortic valve homografts sterilized by electron beam energy.
J Thorac Cardiovasc Surg. 1967 Oct;54(4):471-7.
3
Fluid mechanics of the aortic root with application to coronary flow.
Nature. 1968 Sep 7;219(5158):1059-61. doi: 10.1038/2191059a0.
4
Mechanism of closure of the aortic valve.主动脉瓣关闭机制。
Nature. 1968 Jan 6;217(5123):86-7. doi: 10.1038/217086b0.
5
Replacement of diseased aortic valves with homografts.用同种异体移植物替换病变的主动脉瓣。
Ann Surg. 1969 Jun;169(6):921-6. doi: 10.1097/00000658-196906000-00012.