Low J A
Am J Obstet Gynecol. 1977 May 1;128(1):32-42. doi: 10.1016/0002-9378(77)90292-7.
The bladder-urethral pressure records of 77 patients with involuntary detrusor contractions have been reviewed to described the behavior of the urethra in relation to the involuntary detrusor contraction. The involuntary detrusor contraction is preceded by a fall of urethral pressure in a manner similar to that observed with normal voiding. Parasympathetic blockade will completely or partially prevent the detrusor contraction with a limited effect upon the urethral pressure fall. The meschanism proposed is an interruption of synpathetic effect in the urethra and bladder with parasympathetic stimulation of the detrusor as in normal voiding. The stimulus of this mechanism in the involuntary detrusor contraction is not known; however, a wide range of possibilities should be considered.
回顾了77例逼尿肌不自主收缩患者的膀胱尿道压力记录，以描述尿道在逼尿肌不自主收缩时的表现。逼尿肌不自主收缩之前尿道压力会下降，其方式类似于正常排尿时观察到的情况。副交感神经阻滞将完全或部分阻止逼尿肌收缩，对尿道压力下降的影响有限。提出的机制是，如正常排尿时一样，交感神经对尿道和膀胱的作用中断，同时副交感神经刺激逼尿肌。目前尚不清楚这种机制在逼尿肌不自主收缩中的刺激因素；然而，应考虑多种可能性。
