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小脑浦肯野细胞自发活动的叠加模型。

A superposition model of the spontaneous activity of cerebellar Purkinje cells.

作者信息

Sabah N H, Murphy J T

出版信息

Biophys J. 1971 May;11(5):414-28. doi: 10.1016/S0006-3495(71)86225-2.

DOI:10.1016/S0006-3495(71)86225-2
PMID:5579145
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1483999/
Abstract

Based on physiological evidence for multiple firing zones in the dendritic arborizations of cerebellar Purkinje cells, a superposition model is proposed for spike triggering in these cells. Spike trains from 10 Purkinje cells were analyzed in terms of independence of interspike intervals and the properties of their variance-time curves. The results of this analysis were found consistent with the hypothesis that the spike train of a cerebellar Purkinje cell is the pooled output of a relatively large number of independent component processes. Simplifying assumptions as to the statistical nature of these processes lead to a very rough estimate of the number of firing zones.

摘要

基于小脑浦肯野细胞树突分支中多个放电区的生理学证据,提出了一种用于这些细胞中动作电位触发的叠加模型。根据动作电位间隔的独立性及其方差-时间曲线的特性,分析了来自10个浦肯野细胞的动作电位序列。该分析结果与以下假设一致:小脑浦肯野细胞的动作电位序列是相对大量独立成分过程的汇总输出。对这些过程的统计性质进行简化假设会得出对放电区数量的非常粗略的估计。

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本文引用的文献

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RESPONSE OF NEURONS OF THE SUPERIOR OLIVARY COMPLEX OF THE CAT TO ACOUSTIC STIMULI OF LONG DURATION.猫上橄榄复合体神经元对长时间声刺激的反应
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Activity of Purkinje and basket cells in chronically isolated cerebellar folia.长期分离的小脑小叶中浦肯野细胞和篮状细胞的活性。
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Observations on spike sequences from spontaneously active Purkinje cells in the frog.对青蛙自发活动的浦肯野细胞的峰序列的观察。
Kybernetik. 1965 Jun;2(5):197-205. doi: 10.1007/BF00306415.
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Analysis of electrical potentials evoked in the cerebellar anterior lobe by stimulation of hindlimb and forelimb nerves.通过刺激后肢和前肢神经对小脑前叶诱发的电位进行分析。
Exp Brain Res. 1968;6(3):171-94. doi: 10.1007/BF00235123.
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Input-output relations in computer-simulated nerve cells. Influence of the statistical properties, strength, number and inter-dependence of excitatory pre-synaptic terminals.计算机模拟神经细胞中的输入-输出关系。兴奋性突触前终末的统计特性、强度、数量及相互依赖性的影响。
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Activity of dendrites of single Purkinje cells and its relationship to so-called inactivation response in rabbit cerebellum.兔小脑单个浦肯野细胞树突的活性及其与所谓失活反应的关系。
J Neurophysiol. 1968 Mar;31(2):131-41. doi: 10.1152/jn.1968.31.2.131.
8
The action of a parallel fiber volley on the antidromic invasion of Purkynĕ cells of cat cerebellum.平行纤维群放电对猫小脑浦肯野细胞逆向冲动传入的作用。
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Climbing fibers of cat cerebellum: modulation of activity during sleep.猫小脑的攀缘纤维:睡眠期间活动的调节
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J Neurophysiol. 1969 Nov;32(6):1044-55. doi: 10.1152/jn.1969.32.6.1044.