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小脑浦肯野细胞自发活动的叠加模型。

A superposition model of the spontaneous activity of cerebellar Purkinje cells.

作者信息

Sabah N H, Murphy J T

出版信息

Biophys J. 1971 May;11(5):414-28. doi: 10.1016/S0006-3495(71)86225-2.

Abstract

Based on physiological evidence for multiple firing zones in the dendritic arborizations of cerebellar Purkinje cells, a superposition model is proposed for spike triggering in these cells. Spike trains from 10 Purkinje cells were analyzed in terms of independence of interspike intervals and the properties of their variance-time curves. The results of this analysis were found consistent with the hypothesis that the spike train of a cerebellar Purkinje cell is the pooled output of a relatively large number of independent component processes. Simplifying assumptions as to the statistical nature of these processes lead to a very rough estimate of the number of firing zones.

摘要

基于小脑浦肯野细胞树突分支中多个放电区的生理学证据,提出了一种用于这些细胞中动作电位触发的叠加模型。根据动作电位间隔的独立性及其方差-时间曲线的特性,分析了来自10个浦肯野细胞的动作电位序列。该分析结果与以下假设一致:小脑浦肯野细胞的动作电位序列是相对大量独立成分过程的汇总输出。对这些过程的统计性质进行简化假设会得出对放电区数量的非常粗略的估计。

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