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甲状腺功能亢进症中的红细胞钠

Red cell sodium in hyperthyroidism.

作者信息

Goolden A W, Bateman D, Torr S

出版信息

Br Med J. 1971 Jun 5;2(5761):552-4. doi: 10.1136/bmj.2.5761.552.

DOI:10.1136/bmj.2.5761.552
PMID:5579190
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1795816/
Abstract

A simple method of measuring red cell sodium has shown that about 90% of thyrotoxic patients have values above the upper limit of the normal range. Patients taking 0.3 mg of L-thyroxine daily were found to have a significantly higher mean value for red cell sodium than that of the normal controls. It is suggested that patients taking this amount of thyroxine may be hypermetabolic. The determination of red cell sodium may prove useful as a measure of the peripheral action of thyroid hormone.

摘要

一种测量红细胞钠的简单方法表明,约90%的甲状腺毒症患者的值高于正常范围的上限。发现每日服用0.3毫克L-甲状腺素的患者红细胞钠的平均值显著高于正常对照组。有人提出,服用这种剂量甲状腺素的患者可能处于高代谢状态。红细胞钠的测定可能被证明是一种有用的衡量甲状腺激素外周作用的方法。

相似文献

1
Red cell sodium in hyperthyroidism.甲状腺功能亢进症中的红细胞钠
Br Med J. 1971 Jun 5;2(5761):552-4. doi: 10.1136/bmj.2.5761.552.
2
Red cell sodium and ionic fluxes in patients with hyper- and hypothyroidism.甲状腺功能亢进和减退患者的红细胞钠及离子通量
Korean J Intern Med. 1989 Jan;4(1):18-27. doi: 10.3904/kjim.1989.4.1.18.
3
Red-blood-cell composition in thyroid disease.
Lancet. 1976 Dec 25;2(8000):1382-5. doi: 10.1016/s0140-6736(76)91920-6.
4
Improved endothelial function and lipid profile compensate for impaired hemostatic and inflammatory status in iatrogenic chronic subclinical hyperthyroidism of thyroid cancer patients on L-t4 therapy.在接受左甲状腺素(L-t4)治疗的甲状腺癌患者医源性慢性亚临床甲状腺功能亢进症中,内皮功能和血脂谱的改善弥补了止血和炎症状态的受损。
Exp Clin Endocrinol Diabetes. 2010 Jun;118(6):381-7. doi: 10.1055/s-0029-1224156. Epub 2009 Aug 5.
5
[Sodium and potassium in erythrocytes (author's transl)].
Rinsho Byori. 1973 Aug;21(8):653-7.
6
Erythrocyte sodium/potassium adenosine triphosphatase in thyroid disease and nonthyroidal illness.甲状腺疾病和非甲状腺疾病中的红细胞钠/钾三磷酸腺苷酶
J Clin Endocrinol Metab. 1985 Jul;61(1):110-5. doi: 10.1210/jcem-61-1-110.
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Plasma levels of NT-pro-brain natriuretic peptide in patients with overt and subclinical hyperthyroidism and hypothyroidism.显性和亚临床甲状腺功能亢进症及甲状腺功能减退症患者的血浆 N 端脑利钠肽前体水平。
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[Potassium and sodium concentrations in erythrocytes: Normal values, methods of determination and clinical significance].
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9
[Homologous radioimmunoanalysis of serum L-thyroxine and triiodo-L-thyronine in rats with hypo- and hyperthyroidism].
Rev Esp Fisiol. 1987 Jun;43(2):157-62.
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Flame photometry: a simple method and reference range for erythrocyte sodium and potassium.火焰光度法:一种测定红细胞钠和钾的简单方法及参考范围
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引用本文的文献

1
Peripheral effects of thyroid hormones: alteration of intracellular Na-concentration, ouabain-sensitive Na-transport, and Na-Li countertransport in human red blood cells.甲状腺激素的外周效应:人类红细胞内钠浓度、哇巴因敏感的钠转运及钠-锂逆向转运的改变
Klin Wochenschr. 1984 Jun 15;62(12):598-601. doi: 10.1007/BF01728180.
2
Treatment of hypothyroidism: a reappraisal of thyroxine therapy.甲状腺功能减退症的治疗:甲状腺素治疗的重新评估。
Br Med J. 1973 Jul 21;3(5872):131-4. doi: 10.1136/bmj.3.5872.131.
3
Red cell sodium and ionic fluxes in patients with hyper- and hypothyroidism.甲状腺功能亢进和减退患者的红细胞钠及离子通量
Korean J Intern Med. 1989 Jan;4(1):18-27. doi: 10.3904/kjim.1989.4.1.18.
4
Thyrotropin-induced hyperthyroidism caused by selective pituitary resistance to thyroid hormone. A new syndrome of "inappropriate secretion of TSH".由选择性垂体对甲状腺激素抵抗引起的促甲状腺素诱导的甲状腺功能亢进症。一种“促甲状腺素分泌不当”的新综合征。
J Clin Invest. 1975 Sep;56(3):633-42. doi: 10.1172/JCI108133.
5
The present role of in-vitro tests of thyroid function.
J Clin Pathol. 1975 Mar;28(3):239-43. doi: 10.1136/jcp.28.3.239.

本文引用的文献

1
AN ION TRANSPORT DEFECT IN ERYTHROCYTES FROM UREMIC PATIENTS.尿毒症患者红细胞中的离子转运缺陷。
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2
SPECTROCHEMICAL ANALYSIS OF SODIUM, POTASSIUM, CALCIUM, MAGNESIUM, COPPER, AND ZINC IN NORMAL HUMAN ERYTHROCYTES.正常人红细胞中钠、钾、钙、镁、铜和锌的光谱化学分析
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The assessment of free thyroxine in plasma.血浆中游离甲状腺素的评估。
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Erythrocyte electrolytes in muscle disease.肌肉疾病中的红细胞电解质
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The uptake of radioactive potassium by red cells in various thyroid states.
Clin Sci. 1961 Feb;20:113-22.
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Sodium content of erythrocytes in hyperthyroidism.
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Correction for plasma trapped in the red cell column of the hematocrit.对血细胞比容红细胞柱中滞留的血浆进行校正。
Blood. 1952 Dec;7(12):1227-38.
8
The sodium, potassium, and water contents of red blood cells of healthy human adults.健康成年人红细胞中的钠、钾和水含量。
J Clin Invest. 1966 Nov;45(11):1817-25. doi: 10.1172/JCI105485.
9
Potassium, sodium, and water in normal human red blood cells.正常人体红细胞中的钾、钠和水。
Scand J Clin Lab Invest. 1966;18(2):167-80. doi: 10.3109/00365516609051812.
10
Measurement of the uptake of 99mTc by the thyroid.
Br J Radiol. 1968 Dec;41(492):896-8. doi: 10.1259/0007-1285-41-492-896.