A quantitative approach to the design of antitumor drug dosage schedule via cell cycle kinetics and systems theory.

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作者信息

Kim M, Woo K B, Perry S

出版信息

Ann Biomed Eng. 1977 Mar;5(1):12-33. doi: 10.1007/BF02409336.

DOI:10.1007/BF02409336

PMID:557938

Abstract

摘要

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A quantitative approach to the design of antitumor drug dosage schedule via cell cycle kinetics and systems theory.

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本文引用的文献

Influence of the stage of advancement of leukemia L1210 in mice on the optimal schedule of treatment of cytosine arabinoside (NSC-63878).

Cancer Chemother Rep. 1972 Jun;56(3):327-34.

Basic and therapeutic trial results obtained in the spontaneous AK leukemia (lymphoma) model-end of 1971.

Cancer Chemother Rep. 1972 Jun;56(3):273-87, 289-314.

Effect of 1-beta-D-arabinofuranosylcytosine on cell cycle passage time.

J Natl Cancer Inst. 1970 Nov;45(5):861-7.

Experimental evaluation of potential anticancer agents. XXI. Scheduling of arabinosylcytosine to take advantage of its S-phase specificity against leukemia cells.潜在抗癌剂的实验评估。 XXI. 安排阿糖胞苷给药以利用其对白血病细胞的S期特异性。

Cancer Chemother Rep. 1967 Jun;51(3):125-65.

Chemotherapeutic effects on mammalian tumor cells. 3. Modification of leukemia L1210 growth kinetics with an antimetabolite.

J Natl Cancer Inst. 1966 Jan;36(1):15-20.

Dose schedule and antitumor studies of arabinosyl cytosine (NSC 63878).阿糖胞苷（NSC 63878）的给药方案及抗肿瘤研究

Cancer Res. 1969 Jul;29(7):1325-32.

Comparison of the dose- and timesurvival curves for normal hematopoietic and lymphoma colony-forming cells exposed to vinblastine, vincristine, arabinosylcytosine, and amethopterin.暴露于长春碱、长春新碱、阿糖胞苷和氨甲蝶呤的正常造血和淋巴瘤集落形成细胞的剂量-时间存活曲线比较。

J Natl Cancer Inst. 1969 Jun;42(6):1015-25.

Interphase action of vinblastine and vincristine: differences in their lethal action through the mitotic cycle of cultured mammalian cells.长春碱和长春新碱的间期作用：它们在培养的哺乳动物细胞有丝分裂周期中的致死作用差异。

J Cell Physiol. 1968 Dec;72(3):185-96. doi: 10.1002/jcp.1040720306.

Age responses of cultured mammalian cells to cytotoxic drugs.培养的哺乳动物细胞对细胞毒性药物的年龄反应。

Cancer Res. 1970 May;30(5):1397-408.

Age response to x-radiation of murine lymphoma cells synchronized in vivo.体内同步化的小鼠淋巴瘤细胞对X射线的年龄反应

Proc Natl Acad Sci U S A. 1969 Jul;63(3):686-91. doi: 10.1073/pnas.63.3.686.

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