Bazin H
Ann Immunol (Paris). 1977 Jan-Mar;128(1-2):315-8.
Reaginic immunological responses present characteristics of induction which differentiate them from classical antibodies responses from other classes: among them we studied, on the one hand, the genetic control. In the case of OVO-DNP reaginic antibodies in the rat, the controls exercised by the Ag-B haplotypes or the synthesis loci of the immunoglobulin heavy chains does not seem to be sufficient to explain the experimental results. Another control exist probably. It could be linked to the global IgE serum level control; on the other hand, the IgE plasma cells. In rats infested with Nippostrongylus brasiliensis, they make their appearance in large number in the mesenteric lymph node but not in the lamina propria of the intestinal mucosa.
反应素性免疫反应呈现出一些诱导特征，这些特征将它们与其他类别的经典抗体反应区分开来：在我们研究的这些反应中，一方面是遗传控制。就大鼠中的卵清蛋白 - 二硝基苯酚（OVO - DNP）反应素性抗体而言，由Ag - B单倍型或免疫球蛋白重链的合成位点所行使的控制似乎不足以解释实验结果。可能存在另一种控制。它可能与血清总IgE水平的控制有关；另一方面是IgE浆细胞。在感染巴西日圆线虫的大鼠中，它们大量出现在肠系膜淋巴结中，而不在肠黏膜固有层中。
