Bazin H, Pauwels R
Monogr Allergy. 1979;14:23-6.
IgE and IgD antibodies to ovalbumin were analyzed in animals immunized by three different techniques. The results showed that IgE and IgD immune responses could be induced more or less independently by different immunization schedules. Moreover, the triggering of the IgD membrane receptors of the IgE-B lymphoid cells which seems necessary to obtain a primary reaginic immune response, does not necessarily seem to induce an IgD immune response at the same time. We conclude IgE and IgD circulating antibodies are synthesized by two different B lymphoid cell lines.
通过三种不同技术免疫动物后，分析了针对卵清蛋白的IgE和IgD抗体。结果表明，不同的免疫方案或多或少可独立诱导IgE和IgD免疫反应。此外，获得初次反应性免疫反应似乎必需的IgE-B淋巴细胞的IgD膜受体的触发，不一定同时诱导IgD免疫反应。我们得出结论，IgE和IgD循环抗体是由两种不同的B淋巴细胞系合成的。
