Böhles H J
Klin Padiatr. 1977 Mar;189(2):116-9.
Liver cystathionase activity is absent in the fetal organism. This makes cysteine an essential amino acid for the prematurely born infant. The existing enzyme activity is shifting serine into DNA-synthesis. The placental transfer of cysteine from the mother to the fetus is decreased in comparison to other amino acids. A low fetal cysteine level is giving the shift to DNA-synthesis a further stimulation.
胎儿机体中不存在肝脏胱硫醚酶活性。这使得半胱氨酸成为早产儿的必需氨基酸。现有的酶活性将丝氨酸转化为DNA合成。与其他氨基酸相比,半胱氨酸从母体向胎儿的胎盘转运减少。胎儿半胱氨酸水平较低进一步刺激了向DNA合成的转变。