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2
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Using fos imaging in the rat to reveal the anatomical extent of the disruptive effects of fornix lesions.利用大鼠的Fos成像来揭示穹窿损伤破坏作用的解剖范围。
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双侧穹窿损伤导致的柯萨科夫综合征。

Korsakoff's syndrome resulting from bilateral fornix lesions.

作者信息

Heilman K M, Sypert G W

出版信息

Neurology. 1977 May;27(5):490-3. doi: 10.1212/wnl.27.5.490.

DOI:10.1212/wnl.27.5.490
PMID:558556
Abstract

A patient with a well-circumscribed neoplasm, which destroyed the posterior fornix bilaterally, developed a profound disturbance of recent memory. Unlike previously reported patients who had undergone anterior fornix sections and whose memories were not severely disturbed, this patient's posteriorly located lesion may have cut off hippocampal input into the mamillary bodies and the dorsomesial nucleus, thereby producing a severe amnestic state.

摘要

一名患有边界清晰的肿瘤的患者,该肿瘤双侧破坏了后穹窿,出现了近期记忆的严重障碍。与之前报道的接受前穹窿切开术且记忆未受到严重干扰的患者不同,该患者位于后方的病变可能切断了海马体向乳头体和背内侧核的输入,从而产生了严重的遗忘状态。