Kordová N, Martin C, Wilt J C, Neuman M
Can J Microbiol. 1977 Jun;23(6):649-52. doi: 10.1139/m77-097.
Previous studies on Chlamydia psittaci 6BC propagated in different hosts have shown differences in cytotoxicity but no differences in the ultrastructure of the individual particles. It is shown here that the 6BC strain derived from yolk sac of infected chick embryo sedimented in sucrose gradients at lower densities than the 6BC strain derived from L-cells. Host-related modifications of lipid concentrations of the 6BC strains have been previously documented by others. It is thought that the phenomenon of host-induced modifications of physical properties of the agent might provide a new approach to the study of chlamydial pathogenicity.
先前对在不同宿主中繁殖的鹦鹉热衣原体6BC株的研究表明，其细胞毒性存在差异，但单个颗粒的超微结构没有差异。本文表明，源自感染鸡胚卵黄囊的6BC株在蔗糖梯度中的沉降密度低于源自L细胞的6BC株。其他人之前已经记录了6BC株脂质浓度的宿主相关修饰。据认为，宿主诱导病原体物理性质修饰的现象可能为衣原体致病性的研究提供一种新方法。
