Emmrich P
Institut für Pathologische Anatomie, Universität Leipzig, Deutschland.
Zentralbl Pathol. 1993 Mar;139(1):1-9.
An account is given of morphological issues relating to placental insufficiency. Variable manifestations of placental insufficiency in foetuses and newborns are described in some detail. Reference is made to morphological clues useful in diagnosing causes of placental insufficiency. It proved to be particularly difficult to find quantitatively recordable parameters for such diagnosis, comparable to morphological indicators resulting from various placental measurements or from determination of exchange area and thickness measurement of placental basal membranes. Most of these quantitative methods, after all, would not even be applicable to routine examination. All the other diagnostic criteria of placental insufficiency are part of obstetrics (placental hormone production, measurement of uterus circulation and of intervillous space). In a more specialized section of this paper, reference is made to various pathologico-anatomic patterns of placental disorders and their specific relevance to placental insufficiency. Circulatory disorders (maternal side), placental inflammation, impaired maturation and obliterative endarteriitis were the most common findings in this order.
本文阐述了与胎盘功能不全相关的形态学问题。详细描述了胎儿和新生儿胎盘功能不全的各种表现。提及了有助于诊断胎盘功能不全病因的形态学线索。事实证明,要找到可定量记录的诊断参数非常困难,这些参数要类似于通过各种胎盘测量、交换面积测定或胎盘基底膜厚度测量得出的形态学指标。毕竟,这些定量方法大多甚至不适用于常规检查。胎盘功能不全的所有其他诊断标准都属于产科学范畴(胎盘激素分泌、子宫循环测量和绒毛间隙测量)。在本文更专业的部分,提到了胎盘疾病的各种病理解剖模式及其与胎盘功能不全的特定关联。循环障碍(母体侧)、胎盘炎症、成熟障碍和闭塞性动脉内膜炎是按此顺序最常见的发现。