Campbell R L, Small E W, Lesesne H R, Levin K J, Moore W H
Anesth Analg. 1977 Jul-Aug;56(4):589-93. doi: 10.1213/00000539-197707000-00035.
Hepatitis from halothane is usually diagnosed by excluding other possible causes. Whether preexisting hepatic damage, which can occur in certain autoimmune disorders, contraindicates the use of halothane has yet to be proven. The case of a 14-year-old boy with early-onset juvenile rheumatoid arthritis who developed fatal hepatic necrosis 13 days after halothane anesthesia is presented.
氟烷性肝炎通常通过排除其他可能病因来诊断。某些自身免疫性疾病中可能存在的既往肝损伤是否会成为使用氟烷的禁忌证,尚有待证实。本文报告了一名14岁早发性幼年类风湿关节炎男孩的病例,该男孩在接受氟烷麻醉13天后发生了致命性肝坏死。