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Memory impairment correlates closely with cycloheximide dose and degree of inhibition of protein synthesis.

作者信息

Quinton E E, Kramarcy N R

出版信息

Brain Res. 1977 Aug 5;131(1):184-90. doi: 10.1016/0006-8993(77)90041-5.

DOI:10.1016/0006-8993(77)90041-5
PMID:560240
Abstract
摘要

相似文献

1
Memory impairment correlates closely with cycloheximide dose and degree of inhibition of protein synthesis.记忆损伤与放线菌酮剂量及蛋白质合成抑制程度密切相关。
Brain Res. 1977 Aug 5;131(1):184-90. doi: 10.1016/0006-8993(77)90041-5.
2
Memory impairment during prolonged training in mice given inhibitors of cerebral protein synthesis.给予大脑蛋白质合成抑制剂的小鼠在长时间训练期间的记忆损伤
Brain Res. 1973 Jun 29;56:215-25. doi: 10.1016/0006-8993(73)90336-3.
3
Cycloheximide alters the neural and behavioral responses of mice to electroconvulsive shock.放线菌酮会改变小鼠对电惊厥休克的神经和行为反应。
Brain Res. 1972 Nov 13;46:411-6. doi: 10.1016/0006-8993(72)90031-5.
4
Tyrosine hydroxylase inhibition by cycloheximide and anisomycin is not responsible for their amnesic effect.放线菌酮和茴香霉素对酪氨酸羟化酶的抑制作用与其失忆效应无关。
Brain Res. 1974 Dec 27;82(2):241-8. doi: 10.1016/0006-8993(74)90601-5.
5
[Molecular basis of memory storage: alternative approaches (author's transl)].记忆存储的分子基础：替代方法（作者译）
Tanpakushitsu Kakusan Koso. 1974 Mar;19(3):184-90.
6
Memory impairment after subcutaneous injection of acetoxycycloheximide.皮下注射乙酰氧基环己酰亚胺后的记忆损害
Science. 1968 May 3;160(3827):556-7. doi: 10.1126/science.160.3827.556.
7
[Memory--1. Learning, memory and protein biosynthesis in the brain].[记忆——1. 大脑中的学习、记忆与蛋白质生物合成]
Nihon Rinsho. 1985 Jul;43(7):1308-13.
8
Temporal characteristics of amnesia induced by protein synthesis inhibitor: determination by shock level.蛋白质合成抑制剂诱发失忆的时间特征：由休克水平决定
Nature. 1970 Nov 14;228(5272):677-8. doi: 10.1038/228677a0.
9
Ameliorating effect of emodin, a constitute of Polygonatum multiflorum, on cycloheximide-induced impairment of memory consolidation in rats.黄精成分大黄素对环己酰亚胺诱导的大鼠记忆巩固损伤的改善作用。
J Ethnopharmacol. 2007 Jul 25;112(3):552-6. doi: 10.1016/j.jep.2007.05.004. Epub 2007 May 6.
10
Protein synthesis inhibitors induce both memory impairment and its recovery.蛋白质合成抑制剂既可以引起记忆损伤，也可以诱导其恢复。
Behav Brain Res. 2019 Mar 15;360:202-208. doi: 10.1016/j.bbr.2018.11.046. Epub 2018 Dec 6.

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Fear generalization modulated by shock intensity and protein synthesis inhibitor.恐惧泛化受电击强度和蛋白质合成抑制剂的调节。
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Cycloheximide impairs and enhances memory depending on dose and footshock intensity.
环已酰亚胺的剂量和足底电击强度依赖性地损害和增强记忆。
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Involvement of protein synthesis in the reconsolidation of memory at different time points after formation of conditioned reflex freezing in mice.
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Motor skill learning depends on protein synthesis in motor cortex after training.运动技能学习取决于训练后运动皮层中的蛋白质合成。
J Neurosci. 2004 Jul 21;24(29):6515-20. doi: 10.1523/JNEUROSCI.1034-04.2004.
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Memory consolidation for the discrimination of frequency-modulated tones in mongolian gerbils is sensitive to protein-synthesis inhibitors applied to the auditory cortex.蒙古沙鼠对调频音辨别能力的记忆巩固对应用于听觉皮层的蛋白质合成抑制剂敏感。
Learn Mem. 2002 Sep-Oct;9(5):293-303. doi: 10.1101/lm.47502.
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Protein synthesis inhibition blocks the induction of mossy fiber long-term potentiation in vivo.蛋白质合成抑制可阻断体内苔藓纤维长时程增强的诱导。
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Scopolamine prevents augmentation of stereotypy induced by chronic methamphetamine treatment.
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Utility of an elevated plus-maze for the evaluation of memory in mice: effects of nootropics, scopolamine and electroconvulsive shock.高架十字迷宫在评估小鼠记忆中的效用：益智药、东莨菪碱和电惊厥休克的影响
Psychopharmacology (Berl). 1990;101(1):27-33. doi: 10.1007/BF02253713.