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年龄、性别和昼夜变化对人体纤维蛋白溶解系统的影响。

Effect of age, sex, and diurnal variation on the human fibrinolystic system.

作者信息

Mann R D

出版信息

J Clin Pathol. 1967 May;20(3):223-6. doi: 10.1136/jcp.20.3.223.

Abstract

Fibrinolytic activity, as shown by the dilute blood clot lysis time, tends to show a diurnal variation, but is relatively unaffected by age and sex. Mean plasma anti-urokinase activity is consistently and significantly greater in females in the post-menstrual week than in age-matched males, but is relatively unaffected by daily variation and age. This sex difference in the activity of plasma, which is inhibitory to fibrinolysis, is of a degree which makes this measurement important in studies of the fibrinolytic system in healthy persons and disease states.

摘要

如稀释血凝块溶解时间所示,纤溶活性往往呈现昼夜变化,但相对不受年龄和性别的影响。月经周期后一周女性的平均血浆抗尿激酶活性始终显著高于年龄匹配的男性,但相对不受每日变化和年龄的影响。血浆中这种抑制纤溶的活性存在性别差异,其程度使得该测量在健康人和疾病状态下纤溶系统的研究中具有重要意义。

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