Takemoto M, Arimitsu T, Ueta K, Kuyama H, Miyake I
No Shinkei Geka. 1977 Jun;5(7):733-9.
From January, 1969 to December, 1975, 1700 patients underwent sequential brain scintigraphy with Tc-99-m-pertechnetate. All the scintigrams were obtained on a scintillation camera with high-resolution collimator in our clinic. Intracranial tumors were confirmed in 449 cases and 21 cases out of those were pineal tumors which were diagnosed by clinical symptoms, air study, angiography and Conray-or Myodil-ventriculography. In these pineal tumors, 14 (67%) out of the 21 cases had positive scan on scintigrams. All of our cases of teratoma (one case) and teratocarcinoma (two cases) showed clear abnormal uptake, though it had been reported that they do not tend to have positive results on scintigrams. We also performed scintigraphy on 11 cases out of the 21, both before and after 60Co radiation therapy. In the cases which showed either same grade or more increased abnormal uptake on scintigrams after radiation therapy, compared with that before radiation therapy, compared with that before radiation, their prognoses were poor. On the other hand, those cases which showed decreased abnormal uptake after radiation, have had a healthy daily activities. From these experiences, it may be concluded that brain scintigraphy is clinically valuable not only for making the diagnosis, but for evaluating the effect of radiation therapy and the prognosis in the cases of pineal tumor.
1969年1月至1975年12月，1700例患者接受了锝-99m高锝酸盐序贯脑闪烁扫描。所有闪烁扫描图像均在我院使用配备高分辨率准直器的闪烁相机获得。449例患者确诊为颅内肿瘤，其中21例为松果体肿瘤，通过临床症状、气脑造影、血管造影以及碘卡明或碘苯酯脑室造影确诊。在这些松果体肿瘤患者中，21例中有14例（67%）闪烁扫描图像呈阳性。我们所有的畸胎瘤（1例）和畸胎癌（2例）病例均显示明显的异常摄取，尽管有报道称它们在闪烁扫描中不太容易出现阳性结果。我们还对21例中的11例在60钴放射治疗前后进行了闪烁扫描。与放射治疗前相比，那些在放射治疗后闪烁扫描图像上显示异常摄取程度相同或增加的病例，其预后较差。另一方面，那些放射治疗后异常摄取减少的病例，日常活动正常。从这些经验可以得出结论，脑闪烁扫描不仅在临床上对松果体肿瘤的诊断有价值，而且对评估放射治疗效果和预后也有价值。
