无心畸形

The acardiac anomaly.

作者信息

Benirschke K, des Roches Harper V

出版信息

Teratology. 1977 Jun;15(3):311-6. doi: 10.1002/tera.1420150313.

DOI:10.1002/tera.1420150313

Abstract

Karyotype analysis of a premature human acardiac twin disclosed normal chromosomes. A review of previous cytogenetic, placental and animal studies suggests that chromosomal errors are not the cause of the acardiac anomaly. Rather, they point to the placental vascular anastomoses as the principal pathogenetic event.

摘要

对一名早产无心畸胎的人类双胞胎进行的核型分析显示染色体正常。对先前细胞遗传学、胎盘和动物研究的回顾表明，染色体异常并非无心畸形的病因。相反，这些研究指出胎盘血管吻合是主要的致病事件。