无心畸形的新病例报告及现状。

The acardiac anomaly new case reports and current status.

作者信息

Kaplan C, Benirschke K

出版信息

Acta Genet Med Gemellol (Roma). 1979;28(1):51-9. doi: 10.1017/s0001566000009338.

Abstract

Two cases of holoacardius are presented. Both had a normal 46,XX female karyotype, identical to that of their respective cotwin. Data are presented supporting the concept that the placental vascular anastomoses are the primary agents in the formation of an acardiac. Cytogenetics, epidemiology and other theories of pathogenesis are discussed.

摘要

本文报告了两例无心畸形的病例。两例患者均具有正常的46,XX女性核型，与其各自的双胎之一相同。文中提供的数据支持了胎盘血管吻合是无心畸形形成的主要因素这一观点。同时还讨论了细胞遗传学、流行病学及其他发病机制理论。