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The nature of benzo(a)pyrene-DNA adducts formed in hamster embryo cells depends on the length of time of exposure to benzo(a)pyrene.

作者信息

Baird W M, Diamond L

出版信息

Biochem Biophys Res Commun. 1977 Jul 11;77(1):162-7. doi: 10.1016/s0006-291x(77)80178-2.

DOI:10.1016/s0006-291x(77)80178-2
PMID:560847
Abstract
摘要

相似文献

1
The nature of benzo(a)pyrene-DNA adducts formed in hamster embryo cells depends on the length of time of exposure to benzo(a)pyrene.在仓鼠胚胎细胞中形成的苯并(a)芘-DNA加合物的性质取决于暴露于苯并(a)芘的时间长度。
Biochem Biophys Res Commun. 1977 Jul 11;77(1):162-7. doi: 10.1016/s0006-291x(77)80178-2.
2
Benzo[e]pyrene-induced alterations in the binding of benzo[a]pyrene to DNA in hamster embryo cell cultures.苯并[e]芘诱导仓鼠胚胎细胞培养物中苯并[a]芘与DNA结合的改变。
Carcinogenesis. 1984 Aug;5(8):1065-9. doi: 10.1093/carcin/5.8.1065.
3
Metabolism and macromolecular binding of the carcinogen benzo(a)pyrene and its relatively inert isomer benzo(e)pyrene by hamster embryo cells.仓鼠胚胎细胞对致癌物苯并(a)芘及其相对惰性的异构体苯并(e)芘的代谢和大分子结合
Cancer Res. 1979 Sep;39(9):3463-70.
4
Analysis of benzo(a)pyrene:DNA adducts formed in cells in culture by immobilized boronate chromatography.通过固定化硼酸酯色谱法分析培养细胞中形成的苯并(a)芘:DNA加合物。
Cancer Res. 1984 Sep;44(9):4104-10.
5
Time course of metabolism of benzo[e]pyrene by hamster embryo cells and the effect of chemical modifiers.仓鼠胚胎细胞对苯并[e]芘的代谢时间进程及化学修饰剂的影响。
Chem Biol Interact. 1982 Jul 1;40(3):275-85. doi: 10.1016/0009-2797(82)90151-x.
6
Species- and length of exposure-dependent differences in the benzo(a)pyrene:DNA adducts formed in embryo cell cultures from mice, rats, and hamsters.小鼠、大鼠和仓鼠胚胎细胞培养物中苯并(a)芘:DNA加合物形成的物种及暴露时间依赖性差异。
Cancer Res. 1985 Apr;45(4):1594-600.
7
X-irradiation enhancement of transformation by benzo(a)pyrene in hamster embryo cells.X射线照射增强苯并(a)芘对仓鼠胚胎细胞的转化作用。
Proc Natl Acad Sci U S A. 1971 Aug;68(8):1734-7. doi: 10.1073/pnas.68.8.1734.
8
Benzo[a]pyrene--DNA adduct formation in target cells in a cell-mediated mutation assay.苯并[a]芘——细胞介导突变试验中靶细胞内DNA加合物的形成
Carcinogenesis. 1982;3(11):1317-20. doi: 10.1093/carcin/3.11.1317.
9
DNA and RNA adducts formed in hamster embryo cell cultures exposed to benzo[a]pyrene.暴露于苯并[a]芘的仓鼠胚胎细胞培养物中形成的DNA和RNA加合物。
Biochemistry. 1978 May 2;17(9):1597-603. doi: 10.1021/bi00602a003.
10
Metabolism and macromolecular binding of carcinogenic and noncarcinogenic metabolites of benzo(a)pyrene by hamster embryo cells.仓鼠胚胎细胞对苯并(a)芘致癌和非致癌代谢产物的代谢及大分子结合
Cancer Res. 1980 Feb;40(2):207-11.

引用本文的文献

1
Specificity in interaction of benzo[a]pyrene with nuclear macromolecules: implication of derivatives of two dihydrodiols in protein binding.苯并[a]芘与核大分子相互作用的特异性：两种二氢二醇衍生物在蛋白质结合中的意义。
Proc Natl Acad Sci U S A. 1980 Nov;77(11):6396-400. doi: 10.1073/pnas.77.11.6396.
2
Error-free excision of the cytotoxic,mutagenic N2-deoxyguanosine DNA adduct formed in human fibroblasts by (+/-)-7 beta, 8 alpha-dihydroxy-9 alpha, 10 alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene.人成纤维细胞中由（±）-7β，8α-二羟基-9α，10α-环氧-7,8,9,10-四氢苯并[a]芘形成的具有细胞毒性、致突变性的N2-脱氧鸟苷DNA加合物的无差错切除。
Proc Natl Acad Sci U S A. 1980 Oct;77(10):5933-7. doi: 10.1073/pnas.77.10.5933.
3
Specificity of chemiluminescence in the metabolism of benzo[a]pyrene to its carcinogenic diol epoxide.
苯并[a]芘代谢为其致癌二醇环氧化物过程中化学发光的特异性。
Proc Natl Acad Sci U S A. 1981 Feb;78(2):940-2. doi: 10.1073/pnas.78.2.940.
4
Effect of histone acetylation on the formation and removal of B(a)P chromatin adducts.组蛋白乙酰化对苯并[a]芘染色质加合物形成与去除的影响。
Nucleic Acids Res. 1982 May 11;10(9):2775-89. doi: 10.1093/nar/10.9.2775.
5
Metabolism of benzo[a]pyrene by human mammary epithelial cells: toxicity and DNA adduct formation.人乳腺上皮细胞对苯并[a]芘的代谢：毒性与DNA加合物形成
Proc Natl Acad Sci U S A. 1981 Oct;78(10):6251-5. doi: 10.1073/pnas.78.10.6251.
6
Tumorigenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene 7,8-diol-9,10-epoxides in newborn mice: exceptional activity of (+)-7beta,8alpha-dihydroxy-9alpha,10alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene.非对映体苯并[a]芘7,8 - 二醇 - 9,10 - 环氧化物光学对映体在新生小鼠中的致瘤性：(+)-7β,8α - 二羟基 - 9α,10α - 环氧 - 7,8,9,10 - 四氢苯并[a]芘的异常活性
Proc Natl Acad Sci U S A. 1978 Nov;75(11):5358-61. doi: 10.1073/pnas.75.11.5358.