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[来自小牛胸腺的组蛋白H2B与多头绒泡菌的P4B的同源性]

[Homology of histones H2B from calf thymus and P4B from slime mold Physarum polycephalum].

作者信息

Tyrsin Iu A, Krasheninnikov I A, Tyrsina E G

出版信息

Biokhimiia. 1977 Jun;42(6):1056-61.

PMID:560880
Abstract

A comparative study of the amino acid composition of histone fractions P4b from slime mold Physarum polycephalum and H2B from calf thymus was carried out using peptide mapping. It was shown that 75% of peptides are common for both proteins. The slime mold histones contain two fractions (P4B and P3), which are homologous to the H2B histone fraction of calf thymus. The data of amino acid analysis, peptide mapping and some physico-chemical properties of the histones revealed the following correlation of the two types of histone fractions: P1--H1, P4a--H3, P4b and P3--H2B, P5-H2A, P6--H4.

摘要

利用肽图谱对多头绒泡菌的组蛋白组分P4b和小牛胸腺的H2B的氨基酸组成进行了比较研究。结果表明,两种蛋白质75%的肽是相同的。黏菌组蛋白包含两个组分(P4B和P3),它们与小牛胸腺的H2B组蛋白组分同源。组蛋白的氨基酸分析、肽图谱和一些物理化学性质的数据揭示了两种组蛋白组分的以下相关性:P1--H1,P4a--H3,P4b和P3--H2B,P5-H2A,P6--H4。

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