Vanderhoeft P, Rocmans P
Acta Chir Belg. 1975 Nov;74(6):594-601.
The authors report on a personal series of 27 patients with pulmonary metastases; seventeen were operated, 3 for cure. Nine hundred and eighty six operated cases from the litterature are then analysed yielding the following notions. Where the primary tumor is controlled at the time of metastatic resection, when there is no systemic or mediastinal dissemination, and when the growth of metastases was slow, these secondary resection of lung metastases were followed by a 16 to 63% 5- year survival rate. The authors conclude it is necessary to control the hypothesis that 5 to 10% of operated cancers present a second operative indication for cure: slow growing metastases limited to the lungs.
作者报告了一组27例肺转移患者的个人病例系列;其中17例接受了手术,3例为根治性手术。然后分析了文献中986例手术病例,得出以下观点。当在转移灶切除时原发肿瘤得到控制,没有全身或纵隔扩散,且转移灶生长缓慢时,这些肺转移灶的二次切除术后5年生存率为16%至63%。作者得出结论,有必要验证以下假设:5%至10%的手术癌症存在第二个根治性手术指征,即转移灶生长缓慢且局限于肺部。