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嗜银细胞和潘氏细胞在某些大肠肿瘤中的发生率及意义

Incidence and significance of argentaffin and paneth cells in some tumours of the large intestine.

作者信息

Gibbs N M

出版信息

J Clin Pathol. 1967 Nov;20(6):826-31. doi: 10.1136/jcp.20.6.826.

DOI:10.1136/jcp.20.6.826
PMID:5614067
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC473612/
Abstract

The incidence of argentaffin and Paneth cells in epithelial tumours of the large intestine was investigated. Argentaffin cells were found in adenomatous polyps, villus adenomas, polyposis coli, Peutz-Jehgers' polyps, juvenile polyposis, and adenocarcinomas. Paneth cells were not found in metaplastic or juvenile polyps. The crypt unit was destroyed in neoplasia and argentaffin and Paneth cells occurred either as a result of sequestration or were taking part in the neoplastic process. The crypt unit was retained in the disorders of epithelial growth. The identification of argentaffin and Paneth cells enabled the crypt to be defined and thus provided a useful, practical aid in the differentiation between neoplasms and disorders of epithelial growth.

摘要

对大肠上皮肿瘤中嗜银细胞和潘氏细胞的发生率进行了研究。在腺瘤性息肉、绒毛状腺瘤、结肠息肉病、黑斑息肉病、幼年性息肉病和腺癌中发现了嗜银细胞。在化生息肉或幼年性息肉中未发现潘氏细胞。隐窝单位在肿瘤形成过程中被破坏，嗜银细胞和潘氏细胞的出现要么是隔离的结果，要么是参与了肿瘤形成过程。隐窝单位在上皮生长紊乱中得以保留。嗜银细胞和潘氏细胞的识别使隐窝得以界定，从而为肿瘤与上皮生长紊乱的鉴别提供了有用的实际帮助。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e25/473612/614e86a7d873/jclinpath00371-0036-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e25/473612/164e90450c74/jclinpath00371-0034-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e25/473612/a1603946e930/jclinpath00371-0034-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e25/473612/4f2001947945/jclinpath00371-0034-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e25/473612/99a2aaee21ed/jclinpath00371-0035-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e25/473612/f859f7d54a2b/jclinpath00371-0035-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e25/473612/5efc6bb4099a/jclinpath00371-0036-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e25/473612/614e86a7d873/jclinpath00371-0036-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e25/473612/164e90450c74/jclinpath00371-0034-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e25/473612/a1603946e930/jclinpath00371-0034-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e25/473612/4f2001947945/jclinpath00371-0034-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e25/473612/99a2aaee21ed/jclinpath00371-0035-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e25/473612/f859f7d54a2b/jclinpath00371-0035-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e25/473612/5efc6bb4099a/jclinpath00371-0036-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e25/473612/614e86a7d873/jclinpath00371-0036-b.jpg

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