Rjosk H K, Holzmann K
Geburtshilfe Frauenheilkd. 1977 Aug;37(8):660-4.
Because of the high sensitivity and specificity of the method, radio-immunologic determination of the Beta Subunit HCG in the serum is superior to other methods of monitoring the therapeutic results of the treatment of chorionic carcinoma. A ratio of 225 to 1 of HCG concentrations in the serum versus the cerebral spinal fluid is evidence against the probability of a metastasis of chorionic carcinoma in the central nervous system. Following successful treatment of chorionic carcinoma it is advisable to determine the serum HCG with the Beta Subunit method weekly during the first two months and montly in the succeeding two years and thereafter at three months intervals.
由于该方法具有高灵敏度和特异性，血清中β亚基人绒毛膜促性腺激素（HCG）的放射免疫测定法优于监测绒毛膜癌治疗效果的其他方法。血清与脑脊液中HCG浓度之比为225比1，证明绒毛膜癌转移至中枢神经系统的可能性较小。绒毛膜癌成功治疗后，建议在头两个月每周用β亚基法测定血清HCG，在随后的两年每月测定一次，此后每三个月测定一次。
