Tscherne G
Geburtshilfe Frauenheilkd. 1982 May;42(5):371-5. doi: 10.1055/s-2008-1036778.
Within 10 years 24 patients were treated for choriocarcinoma. Experience with new methods of diagnosis, treatment and followup was gained. 11 patients were considered to be in a low risk group and 13 patients were categorized as high risk patients. The treatment was primarily conservative. Patients with low risk received single treatment with methotrexate. In some cases in the high-risk group combination chemotherapy or polychemotherapy was used. In addition to the clinical findings, the results of the treatment are monitored with serial beta HCG determinations. Of the 11 patients in the low-risk group all well and free of recurrence. Of the high-risk group 6 patients died. Of the total of 24 patients with choriocarcinoma 18 (75%) are well and free of recurrence.
在10年时间里，有24例绒毛膜癌患者接受了治疗。积累了新的诊断、治疗和随访方法的经验。11例患者被认为属于低风险组，13例患者被归类为高风险患者。治疗主要采用保守疗法。低风险患者接受甲氨蝶呤单一治疗。在高风险组的一些病例中，采用了联合化疗或多药化疗。除了临床检查结果外，还通过连续检测β-HCG来监测治疗效果。低风险组的11例患者均情况良好且无复发。高风险组中有6例患者死亡。在总共24例绒毛膜癌患者中，18例（75%）情况良好且无复发。
