Lockart R Z
J Virol. 1967 Dec;1(6):1158-63. doi: 10.1128/JVI.1.6.1158-1163.1967.
Cultures of chick cells exposed to interferon continued to decrease in virus-producing ability during incubation after the interferon was removed. The rate of development of the additional interference and the degree of viral interference finally manifested were dependent on the concentration of interferon to which the cultures were exposed and the time of exposure. Additional interference occurred also in infected cells. Additional interference was inhibited by actinomycin D and puromycin. The best explanation of additional interference is that it results from interferon that is fixed to the cells during their initial period of contact.
暴露于干扰素的鸡细胞培养物在去除干扰素后的孵育过程中，其产生病毒的能力持续下降。额外干扰的发展速度以及最终表现出的病毒干扰程度取决于培养物所暴露的干扰素浓度和暴露时间。额外干扰也发生在受感染的细胞中。放线菌素D和嘌呤霉素可抑制额外干扰。对额外干扰的最佳解释是，它是由细胞在最初接触期间固定的干扰素所致。
