• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

细胞外液量扩张对甲状旁腺切除和完整大鼠无机磷酸盐最大重吸收能力的影响。

Effect of expansion of extracellular fluid volume on the maximal reabsorptive capacity for inorganic phosphate in parathyroidectomized and intact rats.

作者信息

Frick A, Durasin I

出版信息

Pflugers Arch. 1977 Aug 29;370(2):115-9. doi: 10.1007/BF00581683.

DOI:10.1007/BF00581683
PMID:562501
Abstract

Clearance studies were performed in order to examine the effect of expansion of extracellular fluid volume (ECFV) on the maximal reabsorptive capacity for inorganic phosphate (TmPi) in acutely parathyroidectomized (PTX) and intact rats. TmPi values were obtained in both control and volume expansion. In PTX rats, the TmPi values in control and expansion were 8.25 +/- 1.52 and 6.14 +/- 1.02 micronmol/min (mean values +/- S.D.), respectively; the TmPi/GFR values were 2.96 +/- 0.31 and 2.09 +/- 0.30 micronmol/ml, respectively. In intact rats, the TmPi values in control and expansion were 3.56 +/- 0.94 and 2.98 +/- 0.94 micronmol/min, respectively, and the TmPi/GFR values were 1.34 +/- 0.23 and 1.05 +/- 0.23 micronmol/ml, respectively. From these results it is concluded that expansion of ECFV decreases the TmPi values both in the absence and presence of parathyroid hormone.

摘要

为了研究细胞外液量（ECFV）扩张对急性甲状旁腺切除（PTX）大鼠和完整大鼠无机磷酸盐最大重吸收能力（TmPi）的影响，进行了清除率研究。在对照和容量扩张两种情况下均获得了TmPi值。在PTX大鼠中，对照和扩张时的TmPi值分别为8.25±1.52和6.14±1.02微摩尔/分钟（平均值±标准差）；TmPi/GFR值分别为2.96±0.31和2.09±0.30微摩尔/毫升。在完整大鼠中，对照和扩张时的TmPi值分别为3.56±0.94和2.98±0.94微摩尔/分钟，TmPi/GFR值分别为1.34±0.23和1.05±0.23微摩尔/毫升。从这些结果可以得出结论，无论有无甲状旁腺激素，ECFV扩张都会降低TmPi值。

相似文献

1
Effect of expansion of extracellular fluid volume on the maximal reabsorptive capacity for inorganic phosphate in parathyroidectomized and intact rats.细胞外液量扩张对甲状旁腺切除和完整大鼠无机磷酸盐最大重吸收能力的影响。
Pflugers Arch. 1977 Aug 29;370(2):115-9. doi: 10.1007/BF00581683.
2
Maximal reabsorptive capacity for inorganic phosphate (TmPi) in the absence of parathyroid hormone in the rat: decrease of the TmPi during prolonged administration of phosphate and the role of calcium.大鼠在无甲状旁腺激素情况下无机磷酸盐的最大重吸收能力（TmPi）：长期给予磷酸盐期间TmPi的降低及钙的作用
Pflugers Arch. 1978 Oct 18;377(1):9-14. doi: 10.1007/BF00584368.
3
Phosphate excretion in uremic rats: effects of parathyroidectomy and phosphate restriction.尿毒症大鼠的磷酸盐排泄：甲状旁腺切除术和磷酸盐限制的影响。
Am J Physiol. 1985 Feb;248(2 Pt 2):F175-82. doi: 10.1152/ajprenal.1985.248.2.F175.
4
Phosphaturic response of hydrocortisone in the presence and the absence of parathyroid hormone.氢化可的松在有和没有甲状旁腺激素情况下的磷尿反应。
Pflugers Arch. 1981 Dec;392(2):99-105. doi: 10.1007/BF00581256.
5
Acute effects of hydrocortisone on the reabsorption of inorganic phosphate in normal, adrenalectomized and parathyroidectomized rats.氢化可的松对正常、肾上腺切除及甲状旁腺切除大鼠无机磷重吸收的急性影响。
Pflugers Arch. 1979 Nov;382(2):123-6. doi: 10.1007/BF00584212.
6
Localization of parathyroid-hormone-independent sodium bicarbonate inhibition of tubular phosphate reabsorption.甲状旁腺激素非依赖性的肾小管碳酸氢钠对磷酸盐重吸收的抑制作用的定位
Kidney Int. 1980 Jun;17(6):749-55. doi: 10.1038/ki.1980.87.
7
Renal handling of phosphate during extracellular volume expansion and parathyroid hormone administration.细胞外液量扩充及给予甲状旁腺激素期间肾脏对磷酸盐的处理
Miner Electrolyte Metab. 1987;13(5):323-32.
8
Isoproterenol infusion increases the maximal tubular capacity of phosphate reabsorption.输注异丙肾上腺素可增加肾小管对磷酸盐重吸收的最大能力。
Ren Physiol Biochem. 1992 May-Aug;15(3-4):134-40. doi: 10.1159/000173452.
9
Changes in renal phosphate reabsorption in the aged rat.老年大鼠肾磷酸盐重吸收的变化
Proc Soc Exp Biol Med. 1998 May;218(1):62-7. doi: 10.3181/00379727-218-44268.
10
Has vitamin D a direct renal effect on the tubular reabsorption of phosphate? A study in parathyroidectomized (PTX) and non-PTX man.维生素D对肾小管磷酸盐重吸收有直接的肾脏作用吗？一项针对甲状旁腺切除（PTX）和未进行甲状旁腺切除的男性的研究。
Adv Exp Med Biol. 1978;103:111-23. doi: 10.1007/978-1-4684-7758-0_14.

引用本文的文献

1
Renal handling of calcium and phosphate.肾脏对钙和磷的处理。
Klin Wochenschr. 1980 Oct 1;58(19):985-1003. doi: 10.1007/BF01476869.
2
Reabsorption of inorganic sulfate in the rat kidney: evidence for an adaptive depression of TmSO4 during SO4 loading.大鼠肾脏中无机硫酸盐的重吸收：硫酸盐负荷期间TmSO4适应性降低的证据。
Pflugers Arch. 1984 Dec;402(4):433-8. doi: 10.1007/BF00583944.
3
Effect of saline infusion on net reabsorption of endogenous sulfate relative to that of phosphate in intact and thyroparathyroidectomized rats.

本文引用的文献

1
MICROPUNCTURE STUDY OF INORGANIC PHOSPHATE EXCRETION IN THE RAT.大鼠无机磷酸盐排泄的微穿刺研究
J Clin Invest. 1964 Aug;43(8):1596-607. doi: 10.1172/JCI105035.
2
Reabsorption of inorganic phosphate in the rat kidney. I. Saturation of transport mechanism. II. Suppression of fractional phosphate reabsorption due to expansion of extracellular fluid volume.大鼠肾脏中无机磷酸盐的重吸收。I. 转运机制的饱和。II. 细胞外液量增加导致磷酸盐重吸收分数的抑制。
Pflugers Arch. 1968;304(4):351-64. doi: 10.1007/BF00587710.
3
Mechanism of inorganic phosphate diuresis secondary to saline infusions in the rat. Excretion of sodium, inorganic phosphate, and calcium in normal and in parathyroidectomized rats.
在完整大鼠和甲状腺甲状旁腺切除大鼠中，输注生理盐水对内源性硫酸盐相对于磷酸盐净重吸收的影响。
Pflugers Arch. 1986 Apr;406(4):387-91. doi: 10.1007/BF00590941.
4
Maximal reabsorptive capacity for inorganic phosphate (TmPi) in the absence of parathyroid hormone in the rat: decrease of the TmPi during prolonged administration of phosphate and the role of calcium.大鼠在无甲状旁腺激素情况下无机磷酸盐的最大重吸收能力（TmPi）：长期给予磷酸盐期间TmPi的降低及钙的作用
Pflugers Arch. 1978 Oct 18;377(1):9-14. doi: 10.1007/BF00584368.
5
Role of calcium in the decline of phosphate reabsorption during phosphate loading in acutely thyroparathyroidectomized rats.钙在急性甲状旁腺切除大鼠磷酸盐负荷期间磷酸盐重吸收下降中的作用。
Pflugers Arch. 1978 May 31;374(3):249-54. doi: 10.1007/BF00585602.
大鼠中生理盐水输注继发无机磷酸盐利尿的机制。正常及甲状旁腺切除大鼠的钠、无机磷酸盐和钙排泄情况。
Pflugers Arch. 1969;313(2):106-22. doi: 10.1007/BF00586239.
4
Parathormone as a mediator of inorganic phosphate diuresis during saline infusion in the rat.甲状旁腺激素作为大鼠输注生理盐水期间无机磷利尿的介质。
Pflugers Arch. 1971;325(1):1-13. doi: 10.1007/BF00587487.
5
Reabsorption of lithium and phosphate by the rat kidney: role of the parathyroids.大鼠肾脏对锂和磷酸盐的重吸收：甲状旁腺的作用。
Kidney Int. 1974 Mar;5(3):196-203. doi: 10.1038/ki.1974.24.
6
On the mechanism of the phosphaturia of extracellular fluid volume expansion in the dog.关于犬细胞外液量扩张性磷尿的机制
Kidney Int. 1973 Apr;3(4):230-7. doi: 10.1038/ki.1973.36.
7
Effect of saline infusion on phosphate transport in intact and thyroparathyroidectomized rats.盐水输注对完整大鼠和甲状腺甲状旁腺切除大鼠磷酸盐转运的影响。
Am J Physiol. 1973 Dec;225(6):1421-9. doi: 10.1152/ajplegacy.1973.225.6.1421.
8
Decreased phosphate reabsorption by volume expansion in the dog.犬体内容量扩张导致磷酸盐重吸收减少。
Kidney Int. 1972 Nov;2(5):247-52. doi: 10.1038/ki.1972.103.
9
Proximal tubular reabsorption of inorganic phosphate during saline infusion in the rat.大鼠输注生理盐水期间近端肾小管对无机磷酸盐的重吸收
Am J Physiol. 1972 Nov;223(5):1034-40. doi: 10.1152/ajplegacy.1972.223.5.1034.
10
Mechanism of the blunted phosphaturia in saline-loaded thyroparathyroidectomized dogs.生理盐水负荷的甲状旁腺切除犬磷尿症减弱的机制。
Kidney Int. 1974 Jul;6(1):18-23. doi: 10.1038/ki.1974.73.