Olpe H R, Schellenberg H, Koella W P
Eur J Pharmacol. 1977 Oct 1;45(3):291-4. doi: 10.1016/0014-2999(77)90012-7.
GABA and GABA-related drugs such as muscimol, gamma-hydroxybutyric acid and baclofen injected unilaterally into the substantia nigra of rats elicited contraversive turning. Unilateral injections of picrotoxin and bicuculline produced either ipsi- or contraversive turning depending on the volume of vehicle. I.p. applied haloperidol did not abolish the muscimol-induced turning. This and the direction of rotational behavior suggests that the turning behavior elicited by GABA-related drugs is not mediated by the nigrostriatal dopaminergic tract.
γ-氨基丁酸（GABA）以及与GABA相关的药物，如蝇蕈醇、γ-羟基丁酸和巴氯芬，单侧注射到大鼠黑质会引起对侧旋转。单侧注射印防己毒素和荷包牡丹碱会产生同侧或对侧旋转，这取决于溶媒的体积。腹腔注射氟哌啶醇并不能消除蝇蕈醇诱导的旋转。这一点以及旋转行为的方向表明，GABA相关药物引发的旋转行为不是由黑质纹状体多巴胺能通路介导的。
