Tabolin V A, Botvin'ev O K, Chelidze N P
Kardiologiia. 1977 Sep;17(9):74-7.
The blood hydrocortisone and corticosterone content and the aldosterone level in the urine were determined for 24 hours in patients with congenital heart disease before and after operative treatment. In patients with symptoms of cardiac insufficiency both glucocorticoid and mineralocorticoid activity of the adrenal cortex was marked by deviations from the diurnal physiological rhythm. This is reflected in the continuous activation of the adrenal cortex during 24 hours; activation of mineralocorticoid function in the evening and during the night is a particularly characteristic phenomenon.
对先天性心脏病患者在手术治疗前后测定了24小时血中氢化可的松和皮质酮含量以及尿中醛固酮水平。有心脏功能不全症状的患者，肾上腺皮质的糖皮质激素和盐皮质激素活性均显示出与昼夜生理节律的偏差。这表现为肾上腺皮质在24小时内持续激活；傍晚和夜间盐皮质激素功能的激活是一个特别典型的现象。
