[Mineralocorticoid function of the adrenal glands in adolescents with primary arterial hypertension before and after treatment with beta-blocking agents].

A study of adrenal mineral corticoid function in adolescents with primary arterial hypertension, stage Ib, revealed hyperaldosteronism in more than half of the patients (57%). Treatment with beta-blocking agents (anaprilin and obsidan) was only effective (producing a drop in arterial pressure) in patients with initial high plasma aldosterone levels. beta-blocking agents administered to patients with normal blood aldosterone content did not result in arterial pressure change (failure of treatment). The results obtained suggest that the effect of beta-blocking agents on adrenal mineral corticoid activity in adolescent patients with primary arterial hypertension depends on its baseline level; they are also indicative of a dependence of the hypotensive effect of beta-adrenoreceptor blockers on the state of mineral corticoid function.