Mendelson J H
Science. 1968 Jan 19;159(3812):319-20. doi: 10.1126/science.159.3812.319.
Metabolism of ethanol-1-C(14) was assessed in a group of alcoholic and nonalcoholic male subjects. All subjects were screened for absence of physical derangement. Subjects were also carefully matched by dietary, social, and environmental criteria. No differences in rate of output of C(l4)CO(2) were detected after ingestion of alcohol which produced concentrations of 50 to 60 milligrams of alcohol per 100 milliliters of blood. These data do not support the hypothesis that alcoholics metabolize ethanol more rapidly than nonalcoholics do.
在一组酗酒男性和非酗酒男性受试者中评估了乙醇 -1 -C(14)的代谢情况。对所有受试者进行筛查，以确保没有身体紊乱。还根据饮食、社会和环境标准对受试者进行了仔细匹配。摄入酒精后，血液中酒精浓度达到每100毫升50至60毫克时，未检测到C(l4)CO(2)输出速率的差异。这些数据不支持酗酒者比非酗酒者代谢乙醇更快这一假设。
